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Gene · 2784

GNB3: G protein subunit beta 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GNB3: G protein subunit beta 3. Genes, record 2784. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2784

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Gene

Symbol
GNB3
HGNC
Name
G protein subunit beta 3
HGNC
NCBI Gene ID
2784
NCBI Gene
HGNC ID
HGNC:4400
HGNC
Ensembl
ENSG00000111664
NCBI Gene
Aliases
CSNB1H, HG2D
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P16520Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-33402Ensembl, GeneID, HGNC

Source UniProt

Patents48

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026515744 A2026-05-19210P16520Espacenet
JP 2026004568 A2026-01-1448491P16520Espacenet
EP 4640849 A22025-10-2988P16520Espacenet
EP 4641201 A22025-10-29512P16520Espacenet
JP 2025519096 A2025-06-2488P16520Espacenet
JP 2025517969 A2025-06-12512P16520Espacenet
JP 2025032204 A2025-03-1129143P16520Espacenet
EP 4461818 A22024-11-1329143P16520Espacenet
WO 2024214081 A12024-10-17210P16520Espacenet
JP 2023058610 A2023-04-2529143P16520Espacenet

1 to 10 of 48

See all 48 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants954

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGNB3 papersNewest fiscal year
P30DK063491Diabetes Research Center (DRC)42025
R01HL086694From GWAS loci to blood pressure genes, variants & mechanisms - Renewal32025
U54GM104940Louisiana Clinical and Translational Science Center32025
P30CA076292Moffitt Cancer Center Support Grant22025
P30EY000331Vision Research Core at UCLA22025
P30EY014104P30 Core Grant for Vision Research22025
R01EY022305NEIGHBORHOOD Consortium for POAG Genetics22025
ZIAAA000301Integrative genetics of behavior with high throughput technologies22025
ZIAHD002400The Role Of Subclinical Infection And Cytokines In Preterm Parturition22025
ZIAHG200362Genetic epidemiology of complex diseases22025

1 to 10 of 954Source NIH's project files

See all 954 nih grants

Papers1,372

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Genetics of hypertension in populations affected by the Aral Sea ecological crisis: A case-control study.PLoS One202642406770PubTator, text miningPubMed
The GNB3 C825T Polymorphism Is Associated With Decreased Risk of Recurrence of Large-Artery Atherosclerotic Acute Ischemic Stroke.J Am Heart Assoc202642294757PubTator, text miningPubMed
Preeclampsia Genomic Susceptibility Factors in Populations of African Ancestry: A Systematic Review and Meta-Analysis.Int J Mol Sci202641898457PubTator, text miningPubMed
Pharmacology and Pharmacogenomics of Anti-Migraine Drugs.CNS Neurol Disord Drug Targets202641833043PubTator, text miningPubMed
The association between the GNB3 rs5443 C/C genotype and obesity phenotypes in Taiwanese individuals.Biomedicine (Taipei)202641799029PubTator, text miningPubMed
Genetic Architecture of Myopia and Its Implications for Risk Stratification and Prognosis.Diagnostics (Basel)202641750685PubTator, text miningPubMed
The Intersection of m6A Methylation and Immune Response in PCOS: A Bioinformatics Perspective.Immun Inflamm Dis202641725222PubTator, text miningPubMed
The role of gene polymorphisms in the occurrence of gastroesophageal reflux disease: A systematic review and meta-analysis of genetic association studies.Dig Liver Dis202641513492PubTator, text miningPubMed
A genome-wide association study identifies Asian-specific genetic susceptibility for epigenetic age acceleration.Geroscience202640954385PubTator, text miningPubMed
Genetic Scale for Predicting the No-Reflow Phenomenon in Myocardial Infarction.Sovrem Tekhnologii Med202541426969PubTator, text miningPubMed

1 to 10 of 1,372

See all 1,372 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2784

GET https://conductscience.org/api/genes/v1/2784/patents?page=2