ConductScience.org, home

Gene · 279

AMY2A: amylase alpha 2A

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. AMY2A: amylase alpha 2A. Genes, record 279. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/279

On this page

Gene

Symbol
AMY2A
HGNC
Name
amylase alpha 2A
HGNC
NCBI Gene ID
279
NCBI Gene
HGNC ID
HGNC:477
HGNC
Ensembl
ENSG00000243480
NCBI Gene
Aliases
AMY2, PA
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P04746Pancreatic alpha-amylase51151Ensembl, GeneID, HGNC

Source UniProt

Patents77

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026094314 A2026-06-0947P04746Espacenet
JP 2026021360 A2026-02-10138P04746Espacenet
JP 2026004568 A2026-01-1437270P04746Espacenet
EP 4650780 A22025-11-1912858P04746Espacenet
EP 4641201 A22025-10-2914353P04746Espacenet
JP 2025147176 A2025-10-06785P04746Espacenet
JP 2025147176 A2025-10-06786P04746Espacenet
JP 2025529142 A2025-09-045470P04746Espacenet
US 12371689 B22025-07-295470P04746Espacenet
JP 2025517969 A2025-06-1214353P04746Espacenet

1 to 10 of 77

See all 77 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
ACARBOSECHEMBL404271Pancreatic alpha-amylase inhibitorINHIBITOR

Source ChEMBL

Trials57

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

NIH grants291

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleAMY2A papersNewest fiscal year
R35GM133600Repetitive sequences drive genome variation and plasticity32025
U24HG007497Identifying and Characterizing the Full Spectrum of Haplotype-resolved Structural Variation in Human Genomes32025
P20GM139769COBRE in Human Genetics22025
P30CA034196Cancer Center Support (CORE) Grant22025
P30CA054174Mays Cancer Center at UT Health SA22025
P30CA177558University of Kentucky Markey Cancer Center – Cancer Center Support Grant22025
R00GM147352Human centromere variation and function22025
R01CA237159Mechanisms of pancreatic cancer initiation and progression from normal human pancreatic tissue22025
R01CA261934Mobile element mutagenesis as a driver of human cancers22025
R01HG002385Long-read sequence and assembly of segmental duplications22025

1 to 10 of 291Source NIH's project files

See all 291 nih grants

Papers797

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Unfolding the Pharmacological Potentialities and Phytochemical Characterization of Pajanelia longifolia (Wild) Leaves: A Multidimensional Study via GC-MS/MS, In Vitro, In Vivo, and In Silico Approaches.
Chem Biodivers202642571622PubTator, text miningPubMed
Design, synthesis, and biological evaluation of a dichloro-substituted schiff base as an α-amylase inhibitor: structural, computational, and molecular dynamics, in-silico approaches.J Biomol Struct Dyn202642543020PubTator, text miningPubMed
Flavonoid C-glycosides in Fabaceae seeds: From structural diversity and functional significance to human health benefits.Food Chem202642442107PubTator, text miningPubMed
Antidiabetic activity of Cassia javanica flowers through in vitro inhibitory evaluation of α-amylase, α-glucosidase and its antiglycation property.Nat Prod Res202642430509PubTator, text miningPubMed
Novel β-defensin-like marine miniprotein magnificamide-2 with a remarkable potency in inhibiting mammalian α-amylases.Int J Biol Macromol202642419540PubTator, text miningPubMed
Design, synthesis, and biological evaluation of p-thymol-derived 1,2,4-triazole sulfonyl hydrazides as potent α-amylase and α-glucosidase inhiabitors: molecular docking and ADME insights.In Silico Pharmacol202642389728PubTator, text miningPubMed
Coumarin-based small molecules for diabetes management: rational design, computational studies, synthesis, and biological evaluation.J Comput Aided Mol Des202642350715PubTator, text miningPubMed
Design, synthesis, biological evaluation, and in silico characterization of chalcone derivatives as antidiabetic hits.Sci Rep202642342702PubTator, text miningPubMed
In vitro alpha amylase and protein denaturation inhibitory activity of newer generation Schiff base Oxazolone derivatives: Synthesis, chemical characterization, molecular docking, MD simulation, DFT, ADMET, and bioactivity.
Biochem Biophys Res Commun202642330886PubTator, text miningPubMed
Convergent evolution through independent rearrangements in the primate amylase locus.Cell Rep202642184164PubTator, text miningPubMed

1 to 10 of 797

See all 797 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/279

GET https://conductscience.org/api/genes/v1/279/patents?page=2