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Gene · 2806

GOT2: glutamic-oxaloacetic transaminase 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GOT2: glutamic-oxaloacetic transaminase 2. Genes, record 2806. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2806

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Gene

Symbol
GOT2
HGNC
Name
glutamic-oxaloacetic transaminase 2
HGNC
NCBI Gene ID
2806
NCBI Gene
HGNC ID
HGNC:4433
HGNC
Ensembl
ENSG00000125166
NCBI Gene
Aliases
DEE82, KAT4, KATIV, KYAT4, mAspAT, mitAAT
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P00505Aspartate aminotransferase, mitochondrial4303Ensembl, GeneID, HGNC

Source UniProt

Patents53

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4750891 A12026-06-03122P00505Espacenet
JP 2026004568 A2026-01-1447836P00505Espacenet
EP 4650780 A22025-11-191147P00505Espacenet
JP 2025147176 A2025-10-066106P00505Espacenet
JP 2025529142 A2025-09-046523P00505Espacenet
US 12371689 B22025-07-296523P00505Espacenet
JP 2025520609 A2025-07-0326P00505Espacenet
JP 2025517970 A2025-06-121147P00505Espacenet
JP 2025028160 A2025-02-286106P00505Espacenet
KR 1020250010750 A2025-01-216106P00505Espacenet

1 to 10 of 53

See all 53 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,321

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGOT2 papersNewest fiscal year
P30CA008748Cancer Center Support Grant102025
P01CA117969Genetics and Biology of Pancreatic Ductal Adenocarcinoma72025
P30DK048520Colorado Nutrition Obesity Research Center62025
P30DK063491Diabetes Research Center (DRC)52025
P30DK072476Pennington/Louisiana NORC52025
R01DK038389Lipid transport in the intestine52025
P30CA016672Cancer Center Support Grant42025
P30CA030199Cancer Center Support Grant (CCSG)42025
P30CA046934University of Colorado Cancer Center Support Grant42025
P30DK020572Michigan Diabetes Research Center (MDRC)42025

1 to 10 of 2,321Source NIH's project files

See all 2,321 nih grants

Papers3,438

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Distinct Plasma Proteomic Signatures Distinguish MASLD From Non-Steatotic Individuals but Not From MetALD.Liver Int202642809338PubTator, text miningPubMed
A kynurenine immune-metabolic subtype of depression defined by childhood maltreatment and IDO2: Evidence from multi-omics profiling.Psychol Med202642803521PubTator, text miningPubMed
Sub-lethal effects of chemically enhanced water accommodated fraction from marine gas oil on Calanus finmarchicus.Mar Environ Res202642691518PubTator, text miningPubMed
Fatty acid-binding protein 2 in inflammatory bowel disease: mechanistic insights and translational perspectives.Front Med (Lausanne)202642666672PubTator, text miningPubMed
Juvenile Hormone Analogues Reduce the Expression of a Fatty Acid-Binding Protein Involved in Lipid Accumulation in the Migratory Locust Locusta migratoria.Insects202642505775PubTator, text miningPubMed
Migration-associated changes in hormones and muscle physiology of migratory redheaded buntings (Emberiza bruniceps).J Exp Biol202642487633PubTator, text miningPubMed
Proteomic and amino acid profiling of SK-MEL-30 melanoma reveals metabolic and structural changes.Anal Biochem202642470940PubTator, text miningPubMed
Oxaloacetate inhibition of succinate dehydrogenase: mechanism and physiological implications.Am J Physiol Cell Physiol202642370956PubTator, text miningPubMed
Integrating bulk RNA-seq, Mendelian randomization and single-cell RNA-seq to elucidate the roles of lactate metabolism related markers-SLC25A4 and keratinocyte in the pathogenesis of psoriasis.Front Immunol202642292364PubTator, text miningPubMed
Differential expression of metabolic genes distinguishes physiological from pathological cardiac hypertrophy.BMC Cardiovasc Disord202642288718PubTator, text miningPubMed

1 to 10 of 3,438

See all 3,438 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2806

GET https://conductscience.org/api/genes/v1/2806/patents?page=2