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Gene · 2817

GPC1: glypican 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GPC1: glypican 1. Genes, record 2817. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2817

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Gene

Symbol
GPC1
HGNC
Name
glypican 1
HGNC
NCBI Gene ID
2817
NCBI Gene
HGNC ID
HGNC:4449
HGNC
Ensembl
ENSG00000063660
NCBI Gene
Aliases
glypican
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P35052Glypican-15584Ensembl, GeneID, HGNC

Source UniProt

Patents53

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026209808 A12026-10-088P35052Espacenet
JP 2026004568 A2026-01-1448083P35052Espacenet
EP 4650780 A22025-11-192293P35052Espacenet
JP 2025529142 A2025-09-041767P35052Espacenet
US 12371689 B22025-07-291767P35052Espacenet
JP 2025517970 A2025-06-122293P35052Espacenet
WO 2024224052 A12024-10-317P35052Espacenet
JP 2023093161 A2023-07-0443P35052Espacenet
JP 2023086836 A2023-06-2281P35052Espacenet
JP 2023505833 A2023-02-1381P35052Espacenet

1 to 10 of 53

See all 53 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,538

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGPC1 papersNewest fiscal year
ZIABC010891Development of antibody engineering-based cancer therapies142025
P30CA008748Cancer Center Support Grant112025
P30CA062203Cancer Center Support Grant52025
U01DK062481Advancing our Understanding of Rare Pediatric Liver Diseases52025
P30CA006973Regional Oncology Research Center42025
P40OD010440Caenorhabditis Genetics Center42025
U01DK062453Colorado Center of Childhood Liver Disease ResearchNetwork42025
U01DK062497Clinical Center for Cholestatic Liver Disease in Children42025
P30CA013330Cancer Center Support Grant32025
P30CA016058Cancer Center Support Grant32025

1 to 10 of 1,538Source NIH's project files

See all 1,538 nih grants

Papers2,608

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Detection of small extracellular vesicles as biomarkers in tear enabled by shear-horizontal surface acoustic wave biosensor.Talanta202742361474PubTator, text miningPubMed
Immunomagnetic-MXene Bifunctional Probes for Ultrasensitive and Specific Terahertz Metasensing of Tumor-Derived Exosomes.Adv Sci (Weinh)202642814503PubTator, text miningPubMed
Association of Bilateral Vestibulopathy With the ZNF91/LINC01224 Locus: A Genome-Wide Association Study.Neurol Genet202642751493PubTator, text miningPubMed
Glypican-1 in Rhabdomyosarcoma: A Multi-omics Exploration of a Targetable Biomarker.Recent Pat Anticancer Drug Discov202642708284PubTator, text miningPubMed
Advances, challenges, and innovative strategies of CAR-T cell therapy in pancreatic cancer.Biomark Res202642681683PubTator, text miningPubMed
Graph-Based Multi-Omics Integration Reveals Prognostic Histone Modification Reader Genes and Candidate Drug Targets in Colorectal Cancer.Genes (Basel)202642650041PubTator, text miningPubMed
Ginsenoside RD2 inhibits gastric cancer progression by suppressing TRIM46-mediated DUSP1 ubiquitination and modulating the ERK signaling pathway.J Pharmacol Sci202642481127PubTator, text miningPubMed
TDGF1 Mediates the Oncogenic Effects of the OLMALINC/miR-3614-5p ceRNA Axis in Colon Cancer Through Nodal/Smad2 and Glypican-1/MAPK-AKT Signaling.Cells202642439618PubTator, text miningPubMed
Highly Efficient Isolation and Rapid Detection of Pancreatic Cancer-Derived Small Extracellular Vesicles by Specific Aggregation from Aptamer-Functionalized DNA Long Chains.Anal Chem202642438137PubTator, text miningPubMed
Glycocalyx disruption mediates HP-PRRSV-induced microvascular endothelial dysfunction and underlies astragalus polysaccharide's antiviral efficacy.Open Vet J202642375276PubTator, text miningPubMed

1 to 10 of 2,608

See all 2,608 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2817

GET https://conductscience.org/api/genes/v1/2817/patents?page=2