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GPI: glucose-6-phosphate isomerase

1 protein, 94 patents, 0 drugs, 0 trials, 3,770 NIH grants and 8,390 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolGPIHGNC
Nameglucose-6-phosphate isomeraseHGNC
NCBI Gene ID2821NCBI Gene
HGNC IDHGNC:4458HGNC
EnsemblENSG00000105220NCBI Gene
AliasesAMF, CNSHA4, GNPI, NLK, PGI, PHI, SA-36, SA36NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P06744Glucose-6-phosphate isomerase55813Ensembl, GeneID, HGNCUniProt

Patents 94

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1447662P06744Espacenet
EP 4650780 A22025-11-197301P06744Espacenet
JP 2025529142 A2025-09-041771P06744Espacenet
US 12371689 B22025-07-291771P06744Espacenet
JP 2025517970 A2025-06-127301P06744Espacenet
US 12280021 B22025-04-2270P06744Espacenet
US 12269793 B22025-04-0870P06744Espacenet
KR 1020250039524 A2025-03-211P06744Espacenet
EP 4490274 A12025-01-1529P06744Espacenet
EP 4257186 A22023-10-1170P06744Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3770

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant182,025NIH's project files
P30CA008748Cancer Center Support Grant132,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program102,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant82,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase62,025NIH's project files
P30CA177558University of Kentucky Markey Cancer Center – Cancer Center Support Grant62,025NIH's project files
P30CA014195Cancer Center Support Grant (CCSG)52,025NIH's project files
P30CA016087Cancer Center Support Grant52,025NIH's project files
P30CA016520Abramson Cancer Center Support Grant52,025NIH's project files
P30CA068485Cancer Center Support Grant52,025NIH's project files

Papers 8390

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42817136PubTator, text miningPubMed
42813498PubTator, text miningPubMed
42800485PubTator, text miningPubMed
42797401PubTator, text miningPubMed
42793065PubTator, text miningPubMed
42785411PubTator, text miningPubMed
42780545PubTator, text miningPubMed
42774276PubTator, text miningPubMed
42770046PubTator, text miningPubMed
42769816PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license