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Gene · 28234

SLCO1B3: solute carrier organic anion transporter family member 1B3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SLCO1B3: solute carrier organic anion transporter family member 1B3. Genes, record 28234. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/28234

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Gene

Symbol
SLCO1B3
HGNC
Name
solute carrier organic anion transporter family member 1B3
HGNC
NCBI Gene ID
28234
NCBI Gene
HGNC ID
HGNC:10961
HGNC
Ensembl
ENSG00000111700
NCBI Gene
Aliases
HBLRR, LST-2, LST-3TM13, LST3, OATP-8, OATP1B3, OATP8, SLC21A8
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9NPD5Solute carrier organic anion transporter family member 1B37021Ensembl, GeneID, HGNC

Source UniProt

Patents44

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026067851 A2026-04-21379Q9NPD5Espacenet
JP 2026004568 A2026-01-1464890Q9NPD5Espacenet
JP 2026004568 A2026-01-1464891Q9NPD5Espacenet
EP 4641201 A22025-10-291435Q9NPD5Espacenet
JP 2025529142 A2025-09-044327Q9NPD5Espacenet
US 12371689 B22025-07-294327Q9NPD5Espacenet
JP 2025517969 A2025-06-121435Q9NPD5Espacenet
EP 4556017 A12025-05-211Q9NPD5Espacenet
JP 2023521663 A2023-05-25378Q9NPD5Espacenet
US 11446398 B22022-09-2082285Q9NPD5Espacenet

1 to 10 of 44

See all 44 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants987

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSLCO1B3 papersNewest fiscal year
R35GM122576Mechanisms of Altered Hepatic Transport: Impact on Drug Therapy152025
P30CA021765Cancer Center Support Grant (CCSG)122025
P30ES006694Southwest Environmental Health Sciences Center112025
P50CA097186The Pacific Northwest Prostate Cancer SPORE102025
ZIABC010453Genetics and Molecular Mechanisms of Prostate Cancer102025
ZIABC010627Clinical Pharmacogenetics102025
T32ES007091Training in Environmental Toxicology of Human Disease92025
U24CA247648The Chesapeake-Ohio Pharmacokinetics Core for The ETCTN92025
P30DK026743UCSF Liver Center82025
P01CA163227Androgen Receptor Action in Castration Resistant Prostate Cancer72025

1 to 10 of 987Source NIH's project files

See all 987 nih grants

Papers2,854

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
[Analysis a patient with Dubin-Johnson syndrome due to a rare c.4120C>T nonsense variant of ABCC2 gene].Zhonghua Yi Xue Yi Chuan Xue Za Zhi202642711131PubTator, text miningPubMed
Physiologically Based Pharmacokinetic Modeling to Assess Transporter-Mediated Drug-Drug Interactions in Support of Labeling Recommendations for Zavegepant Nasal Spray.Clin Pharmacol Ther202642698006PubTator, text miningPubMed
In vitro assessments for pharmacokinetic drug-drug interaction potential of vornorexant, a novel dual orexin 1/2 receptor antagonist.Xenobiotica202642693680PubTator, text miningPubMed
Impact of SLCO1B3 767G>C (rs60140950) polymorphism on paclitaxel response in Iraqi women with breast cancer.J Taibah Univ Med Sci202642676853PubTator, text miningPubMed
Identification of Gln422 in transmembrane domain 9 as a key amino acid residue for the selective transport of ginsenoside Re by organic anion transporting polypeptide 1B3.Drug Metab Dispos202642664884PubTator, text miningPubMed
Clinical and Genetic Determinants of Hepatocellular Carcinoma in a Turkish Cohort: Impact of SLCO1B1 and SLCO1B3 Germline Variations and Demographic Risk Factors.Int J Mol Sci202642511559PubTator, text miningPubMed
Transcriptomics-driven non-invasive liquid biopsy for diagnosing peritoneal lavage cytology-positive gastric cancer.NPJ Precis Oncol202642457866PubTator, text miningPubMed
Pediatric acute liver failure in a child with arsenic toxicity and underlying rotor syndrome.Oxf Med Case Reports202642422268PubTator, text miningPubMed
Serum benzylpenicillin levels during treatment for amatoxin poisoning: pharmacokinetic support for OATP1B3 inhibition.Clin Toxicol (Phila)202642396640PubTator, text miningPubMed
Quantification of Binding of Small Molecules to Native Kinases by Flow Cytometry Reveals Divergence from Biochemical Affinities.J Am Chem Soc202642336767PubTator, text miningPubMed

1 to 10 of 2,854

See all 2,854 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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