Gene · 282616
IFNL2: interferon lambda 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. IFNL2: interferon lambda 2. Genes, record 282616. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/282616
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q8IZJ0 | Interferon lambda-2 | 200 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents135
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| US 12534732 B2 | 2026-01-27 | 914 | Q8IZJ0 | Espacenet |
| JP 2026012378 A | 2026-01-23 | 914 | Q8IZJ0 | Espacenet |
| US 12516329 B2 | 2026-01-06 | 914 | Q8IZJ0 | Espacenet |
| EP 4670792 A2 | 2025-12-31 | 914 | Q8IZJ0 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 6032 | Q8IZJ0 | Espacenet |
| KR 1020250160362 A | 2025-11-12 | 914 | Q8IZJ0 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 6757 | Q8IZJ0 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6664 | Q8IZJ0 | Espacenet |
| JP 2025524620 A | 2025-07-30 | 373 | Q8IZJ0 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6664 | Q8IZJ0 | Espacenet |
1 to 10 of 135
See all 135 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,310
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | IFNL2 papers | Newest fiscal year |
|---|---|---|---|
| P30DK034854 | Integrated Epithelial and Muscosal Biology | 9 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 8 | 2025 |
| R01AI121066 | Innate control of the inflammatory process during fungal infections | 7 | 2025 |
| R01DK115217 | Type III interferon Control of Mucosal Immunity | 7 | 2025 |
| UL1TR001866 | Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success | 7 | 2025 |
| U19AI095227 | Viral and Host Determinants of Infant and Childhood Allergy and Asthma | 5 | 2025 |
| P30AI094189 | The Johns Hopkins Center for AIDS Research (JHU CFAR) | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| P30DK052574 | Host-environment interactions in the pathophysiology of digestive disease | 4 | 2025 |
| R01AR071384 | Characterization of interferon kappa as a novel target in cutaneous lupus | 4 | 2025 |
1 to 10 of 1,310Source NIH's project files
See all 1,310 nih grantsPapers1,810
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Differential host responses by the type I and III interferons in primary differentiated human nasal epithelial cells are a determinant of antiviral activity. | Front Pharmacol | 2026 | 42812250 | PubTator, text mining | PubMed |
| Perioperative Inflammatory Cytokine Profiles in Patients with Atrial Fibrillation Undergoing Catheter Treatment: A Prospective Observational Study from Kazakhstan. | J Clin Med | 2026 | 42452724 | PubTator, text mining | PubMed |
| Interferon lambda in anti-viral defense and cancer: dual roles, mechanism and therapeutic potential. | J Transl Med | 2026 | 42092929 | PubTator, text mining | PubMed |
| Refining biomarker-based clustering of cardiovascular inflammatory phenotypes in HIV using Recursive Feature Addition: A comparative evaluation approach. | PLoS Comput Biol | 2026 | 42044089 | PubTator, text mining | PubMed |
| Imbalance of type I and II interferon pathways is associated with pain perception in Sjogren's disease: a real-life study. | Front Immunol | 2026 | 42039197 | PubTator, text mining | PubMed |
| Interferon dynamics in deltaretroviruses: why HTLV-1 evades, but BLV responds. | Mol Biol Rep | 2026 | 41920397 | PubTator, text mining | PubMed |
| Monkeypox virus replication and host response in vaginal and ectocervical epithelial cells. | Virulence | 2026 | 41880196 | PubTator, text mining | PubMed |
| A genus-wide interaction atlas across NS4B orthologues identifies a conserved role for UFMylation in orthoflavivirus replication. | Nat Commun | 2026 | 41826287 | PubTator, text mining | PubMed |
| MERS-CoV and SARS-CoV-1 proteins inhibit the IFN-α JAK/STAT pathway of epithelial cells, via IFN-λ-induced USP18. | Front Immunol | 2026 | 41798916 | PubTator, text mining | PubMed |
| Differential antiviral effects and immune responses in nasal and airway organoid during RSV infection: implications for interferon therapy. | Front Immunol | 2026 | 41789060 | PubTator, text mining | PubMed |
1 to 10 of 1,810
See all 1,810 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/282616
GET https://conductscience.org/api/genes/v1/282616/patents?page=2