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IFNL3: interferon lambda 3

1 protein, 72 patents, 0 drugs, 0 trials, 2,199 NIH grants and 5,207 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolIFNL3HGNC
Nameinterferon lambda 3HGNC
NCBI Gene ID282617NCBI Gene
HGNC IDHGNC:18365HGNC
EnsemblENSG00000197110NCBI Gene
AliasesIFN-lambda-3, IFN-lambda-4, IL-28B, IL-28C, IL28B, IL28CNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q8IZI9Interferon lambda-31963Ensembl, GeneID, HGNCUniProt

Patents 72

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
US 12534732 B22026-01-27915Q8IZI9Espacenet
JP 2026012378 A2026-01-23915Q8IZI9Espacenet
US 12516329 B22026-01-06915Q8IZI9Espacenet
EP 4670792 A22025-12-31915Q8IZI9Espacenet
EP 4650780 A22025-11-1913552Q8IZI9Espacenet
KR 1020250160362 A2025-11-12915Q8IZI9Espacenet
JP 2025147176 A2025-10-066759Q8IZI9Espacenet
JP 2025529142 A2025-09-046665Q8IZI9Espacenet
JP 2025524620 A2025-07-30370Q8IZI9Espacenet
JP 2025524620 A2025-07-30371Q8IZI9Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2199

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30DK026743UCSF Liver Center332,025NIH's project files
U19AI082630Durable Alteration of the Human Immune system after Infection or Immunotherapy272,025NIH's project files
R01AI078881Collaborative Integration of HCV Molecular Virology and Mathematical Modeling182,025NIH's project files
ZIACL009010DC Partnership for HIV/AIDS Progress (DC PFAP)182,025NIH's project files
ZIACP005782Epidemiology of Oncogenic Viruses182,025NIH's project files
ZIADK054505Therapy, Vaccine and Model Development in Viral Hepatitis and Liver Diseases152,025NIH's project files
ZIADK075009Natural History, Therapy and Pathogenesis of Chronic Viral Hepatitis C142,025NIH's project files
ZIADK054503Molecular Approaches To Antiviral Development For Viral Hepatitis and Other Viral Diseases122,025NIH's project files
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success112,025NIH's project files
T32DK060414NRSA Hepatology Training Grant92,025NIH's project files

Papers 5207

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42766635PubTator, text miningPubMed
42762643PubTator, text miningPubMed
42710444PubTator, text miningPubMed
42650779PubTator, text miningPubMed
42645607PubTator, text miningPubMed
42502946PubTator, text miningPubMed
42307189PubTator, text miningPubMed
42213608PubTator, text miningPubMed
42150851PubTator, text miningPubMed
42135777PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license