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Gene · 282618

IFNL1: interferon lambda 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. IFNL1: interferon lambda 1. Genes, record 282618. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/282618

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Gene

Symbol
IFNL1
HGNC
Name
interferon lambda 1
HGNC
NCBI Gene ID
282618
NCBI Gene
HGNC ID
HGNC:18363
HGNC
Ensembl
ENSG00000182393
NCBI Gene
Aliases
IL-29, IL29
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q8IU54Interferon lambda-12002Ensembl, GeneID, HGNC

Source UniProt

Patents163

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4740966 A12026-05-13178Q8IU54Espacenet
EP 4650780 A22025-11-195834Q8IU54Espacenet
US 12473363 B22025-11-18925Q8IU54Espacenet
JP 2025147176 A2025-10-066756Q8IU54Espacenet
JP 2025529142 A2025-09-046663Q8IU54Espacenet
JP 2025524620 A2025-07-30369Q8IU54Espacenet
US 12371689 B22025-07-296663Q8IU54Espacenet
WO 2025151800 A12025-07-17369Q8IU54Espacenet
WO 2025151803 A12025-07-17369Q8IU54Espacenet
JP 2025517970 A2025-06-125834Q8IU54Espacenet

1 to 10 of 163

See all 163 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,139

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleIFNL1 papersNewest fiscal year
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success222025
P30DK034854Integrated Epithelial and Muscosal Biology82025
U19AI082630Durable Alteration of the Human Immune system after Infection or Immunotherapy82025
P30CA008748Cancer Center Support Grant72025
R01AI121066Innate control of the inflammatory process during fungal infections72025
R01DK115217Type III interferon Control of Mucosal Immunity72025
P30AI050409Center for AIDS Research at Emory University62025
P30CA046934University of Colorado Cancer Center Support Grant62025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant62025
R01AR071384Characterization of interferon kappa as a novel target in cutaneous lupus62025

1 to 10 of 2,139Source NIH's project files

See all 2,139 nih grants

Papers3,423

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Differential host responses by the type I and III interferons in primary differentiated human nasal epithelial cells are a determinant of antiviral activity.Front Pharmacol202642812250PubTator, text miningPubMed
Spatial characterization of interface dermatitis in cutaneous lupus reveals novel chemokine axis-mediated recruitment of leukocytes that drive disease.Sci Rep202642744872PubTator, text miningPubMed
Corrigendum to "IFNL1 gene promoter single nucleotide polymorphism rs7247086 enhances transcription through a STAT-binding site" [Cytokine 207 (2026) 157200].Cytokine202642692936PubTator, text miningPubMed
IFNL1 gene promoter single nucleotide polymorphism rs7247086 enhances transcription through a STAT-binding site.Cytokine202642604633PubTator, text miningPubMed
Exploratory Longitudinal Pilot Study of Proteomic and Metabolomic Profiling Suggests a Hypothesized PIAS4-NF-κB-Stearic Acid Model in Atypical Depression.Curr Neuropharmacol202642576580PubTator, text miningPubMed
Single-cell heterogeneity in interferon induction potential is heritable and governed by variation in cell state.Cell Syst202642462718PubTator, text miningPubMed
Rhinovirus infection may contribute to esophageal inflammation in eosinophilic esophagitis.J Leukoc Biol202642430666PubTator, text miningPubMed
Ligation of the CD163 molecule inhibits the synthesis of type I and type III interferons in porcine alveolar macrophages.BMC Vet Res202642410590PubTator, text miningPubMed
From acute mast cell activation to a structured immunothrombotic and autoimmune niche in chronic spontaneous urticaria.Inflamm Res202642393364PubTator, text miningPubMed
Serum profile of IL-29, IL-41, and raftlin in microvascular complications of type 2 diabetes mellitus.Sci Rep202642304031PubTator, text miningPubMed

1 to 10 of 3,423

See all 3,423 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/282618

GET https://conductscience.org/api/genes/v1/282618/patents?page=2