Gene · 282618
IFNL1: interferon lambda 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. IFNL1: interferon lambda 1. Genes, record 282618. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/282618
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q8IU54 | Interferon lambda-1 | 200 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents163
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4740966 A1 | 2026-05-13 | 178 | Q8IU54 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 5834 | Q8IU54 | Espacenet |
| US 12473363 B2 | 2025-11-18 | 925 | Q8IU54 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 6756 | Q8IU54 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6663 | Q8IU54 | Espacenet |
| JP 2025524620 A | 2025-07-30 | 369 | Q8IU54 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6663 | Q8IU54 | Espacenet |
| WO 2025151800 A1 | 2025-07-17 | 369 | Q8IU54 | Espacenet |
| WO 2025151803 A1 | 2025-07-17 | 369 | Q8IU54 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 5834 | Q8IU54 | Espacenet |
1 to 10 of 163
See all 163 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,139
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | IFNL1 papers | Newest fiscal year |
|---|---|---|---|
| UL1TR001866 | Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success | 22 | 2025 |
| P30DK034854 | Integrated Epithelial and Muscosal Biology | 8 | 2025 |
| U19AI082630 | Durable Alteration of the Human Immune system after Infection or Immunotherapy | 8 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 7 | 2025 |
| R01AI121066 | Innate control of the inflammatory process during fungal infections | 7 | 2025 |
| R01DK115217 | Type III interferon Control of Mucosal Immunity | 7 | 2025 |
| P30AI050409 | Center for AIDS Research at Emory University | 6 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 6 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 6 | 2025 |
| R01AR071384 | Characterization of interferon kappa as a novel target in cutaneous lupus | 6 | 2025 |
1 to 10 of 2,139Source NIH's project files
See all 2,139 nih grantsPapers3,423
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Differential host responses by the type I and III interferons in primary differentiated human nasal epithelial cells are a determinant of antiviral activity. | Front Pharmacol | 2026 | 42812250 | PubTator, text mining | PubMed |
| Spatial characterization of interface dermatitis in cutaneous lupus reveals novel chemokine axis-mediated recruitment of leukocytes that drive disease. | Sci Rep | 2026 | 42744872 | PubTator, text mining | PubMed |
| Corrigendum to "IFNL1 gene promoter single nucleotide polymorphism rs7247086 enhances transcription through a STAT-binding site" [Cytokine 207 (2026) 157200]. | Cytokine | 2026 | 42692936 | PubTator, text mining | PubMed |
| IFNL1 gene promoter single nucleotide polymorphism rs7247086 enhances transcription through a STAT-binding site. | Cytokine | 2026 | 42604633 | PubTator, text mining | PubMed |
| Exploratory Longitudinal Pilot Study of Proteomic and Metabolomic Profiling Suggests a Hypothesized PIAS4-NF-κB-Stearic Acid Model in Atypical Depression. | Curr Neuropharmacol | 2026 | 42576580 | PubTator, text mining | PubMed |
| Single-cell heterogeneity in interferon induction potential is heritable and governed by variation in cell state. | Cell Syst | 2026 | 42462718 | PubTator, text mining | PubMed |
| Rhinovirus infection may contribute to esophageal inflammation in eosinophilic esophagitis. | J Leukoc Biol | 2026 | 42430666 | PubTator, text mining | PubMed |
| Ligation of the CD163 molecule inhibits the synthesis of type I and type III interferons in porcine alveolar macrophages. | BMC Vet Res | 2026 | 42410590 | PubTator, text mining | PubMed |
| From acute mast cell activation to a structured immunothrombotic and autoimmune niche in chronic spontaneous urticaria. | Inflamm Res | 2026 | 42393364 | PubTator, text mining | PubMed |
| Serum profile of IL-29, IL-41, and raftlin in microvascular complications of type 2 diabetes mellitus. | Sci Rep | 2026 | 42304031 | PubTator, text mining | PubMed |
1 to 10 of 3,423
See all 3,423 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/282618
GET https://conductscience.org/api/genes/v1/282618/patents?page=2