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Gene · 2829

XCR1: X-C motif chemokine receptor 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. XCR1: X-C motif chemokine receptor 1. Genes, record 2829. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2829

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Gene

Symbol
XCR1
HGNC
Name
X-C motif chemokine receptor 1
HGNC
NCBI Gene ID
2829
NCBI Gene
HGNC ID
HGNC:1625
HGNC
Ensembl
ENSG00000173578
NCBI Gene
Aliases
CCXCR1, GPR5
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P46094Chemokine XC receptor 13331Ensembl, GeneID, HGNC

Source UniProt

Patents78

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4803546 A12026-09-0939P46094Espacenet
JP 2026004568 A2026-01-1440991P46094Espacenet
JP 2026004568 A2026-01-1440993P46094Espacenet
EP 4641201 A22025-10-294248P46094Espacenet
EP 4641202 A22025-10-29252P46094Espacenet
JP 2025529142 A2025-09-045273P46094Espacenet
JP 2025524662 A2025-07-307P46094Espacenet
US 12371689 B22025-07-295273P46094Espacenet
JP 2025517969 A2025-06-124248P46094Espacenet
EP 4555326 A22025-05-217P46094Espacenet

1 to 10 of 78

See all 78 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,173

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleXCR1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant82025
P30CA091842Cancer Center Support Grant82025
U19AI128949Human anti-viral immune responses in tissues and circulation62025
R37AI058072Structural Basis for Chemokine Function52025
P30CA016087Cancer Center Support Grant42025
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital42025
R37AI072571Molecular Control of Plasmacytoid Dendritic Cell Development and Function42025
UL1TR002345Washington University Institute of Clinical and Translational Sciences42025
I01BX000656Immunoregulatory Mechanisms to Combat CNS Pathology During Infection32025
P30CA016056Roswell Park Cancer Center Support Grant32025

1 to 10 of 1,173Source NIH's project files

See all 1,173 nih grants

Papers1,709

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
The Bile Acid Signaling Axis: Deciphering the Roles of FXR and TGR5 in Hepatic Steatosis, Fibrosis, and Cancer.Pharmacol Res Perspect202642811458PubTator, text miningPubMed
Canonical and isomiR products of miR-142 enhance dendritic cell reprogramming.Cell Rep202642593968PubTator, text miningPubMed
Association of chemokine and chemokine receptor gene variants with occurrence of multiple primary melanoma.Melanoma Res202642550086PubTator, text miningPubMed
Personalized tumor-loaded monocyte-derived dendritic cell vaccination in combination with atezolizumab as maintenance treatment in extensive-stage small cell lung cancer (ES-SCLC): phase Ib-II VENEZOLUNG trial.
J Immunother Cancer202642498486PubTator, text miningPubMed
SBRT embedded in low-dose RT plus αPD-1 (immuno-EclipseRT, iERT) elicits CD8+ T cell immunity against bulky tumors via an IFN-I/NK/DC axis.Nat Commun202642420294PubTator, text miningPubMed
dNK3 cells in normal pregnancy and recurrent pregnancy loss: from molecular identity to functional imbalance.Front Immunol202642212143PubTator, text miningPubMed
A cDC1-NK/T-Malignant Cell Circuit Drives Immunogenic Remodeling Under PD-1 Blockade in Gastric Cancer.Cancer Sci202642166535PubTator, text miningPubMed
Shared autonomous HERV loci transcription identifies a unique circulating CD14+-xCR1+ mononuclear cell phenotype in a patient group with post-acute sequelae of COVID-19.PLoS One202642154742PubTator, text miningPubMed
Homeostatic mature dendritic cells instruct fibroblast specialization via Notch2 signaling to establish T cell niches.Immunity202642030954PubTator, text miningPubMed
Dual-chemokine-armed oncolytic Senecavirus A co-recruits cDC1 and CXCR3+ T cells to convert 'cold' melanoma and drive durable regression.J Immunother Cancer202641916730PubTator, text miningPubMed

1 to 10 of 1,709

See all 1,709 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2829

GET https://conductscience.org/api/genes/v1/2829/patents?page=2