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ANGPT1: angiopoietin 1

1 protein, 243 patents, 2 drugs, 29 trials, 4,287 NIH grants and 9,605 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolANGPT1HGNC
Nameangiopoietin 1HGNC
NCBI Gene ID284NCBI Gene
HGNC IDHGNC:484HGNC
EnsemblENSG00000154188NCBI Gene
AliasesAGP1, AGPT, AGPT-1, ANG1, Ang1, HAE5, KIAA0003NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q15389Angiopoietin-14985Ensembl, GeneID, HGNCUniProt

Patents 243

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
US 12624098 B22026-05-1226Q15389Espacenet
JP 2026500184 A2026-01-0610Q15389Espacenet
JP 2025538460 A2025-11-281Q15389Espacenet
EP 4650780 A22025-11-1915115Q15389Espacenet
EP 4641201 A22025-10-2917981Q15389Espacenet
KR 1020250152054 A2025-10-221Q15389Espacenet
KR 1020250152058 A2025-10-2210Q15389Espacenet
EP 4630022 A12025-10-1510Q15389Espacenet
JP 2025147176 A2025-10-06803Q15389Espacenet
EP 4619012 A12025-09-241Q15389Espacenet

Drugs 2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
AMG-780CHEMBL2109586Angiopoietin-1 inhibitorINHIBITORChEMBL
TREBANANIBCHEMBL2108568Angiopoietin-1 inhibitorINHIBITORChEMBL

Trials 29

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT03239145TREBANANIBPHASE12026-03-12ClinicalTrials.gov
NCT02525536TREBANANIBPHASE12015-09-22ClinicalTrials.gov
NCT01907308TREBANANIBPHASE2ClinicalTrials.gov
NCT01666977TREBANANIBPHASE1/PHASE2ClinicalTrials.gov
NCT01664182TREBANANIBPHASE22022-06-07ClinicalTrials.gov
NCT01623869TREBANANIBPHASE22015-07-02ClinicalTrials.gov
NCT01609790TREBANANIBPHASE22017-02-27ClinicalTrials.gov
NCT01555268TREBANANIBPHASE1ClinicalTrials.gov
NCT01553188TREBANANIBPHASE22018-10-16ClinicalTrials.gov
NCT01548482TREBANANIBPHASE1ClinicalTrials.gov

NIH grants 4287

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant372,025NIH's project files
P30CA008748Cancer Center Support Grant132,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award122,025NIH's project files
P30CA068485Cancer Center Support Grant112,025NIH's project files
P30CA006973Regional Oncology Research Center92,025NIH's project files
P30CA060553The Robert H. Lurie Comprehensive Cancer Center92,025NIH's project files
P30EY016665Core Grant for Vision Research92,025NIH's project files
P30EY014104P30 Core Grant for Vision Research72,025NIH's project files
R01HL076485Engineering Vascularized Cardiac Muscle72,025NIH's project files
T32CA101642Training of Academic Gynecologic Oncologists72,025NIH's project files

Papers 9605

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42823170PubTator, text miningPubMed
42793172PubTator, text miningPubMed
42787653PubTator, text miningPubMed
42764272PubTator, text miningPubMed
42732598PubTator, text miningPubMed
42724281PubTator, text miningPubMed
42699750PubTator, text miningPubMed
42668950PubTator, text miningPubMed
42667986PubTator, text miningPubMed
42652951PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license