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Gene · 284217

LAMA1: laminin subunit alpha 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. LAMA1: laminin subunit alpha 1. Genes, record 284217. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/284217

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Gene

Symbol
LAMA1
HGNC
Name
laminin subunit alpha 1
HGNC
NCBI Gene ID
284217
NCBI Gene
HGNC ID
HGNC:6481
HGNC
Ensembl
ENSG00000101680
NCBI Gene
Aliases
LAMA, PTBHS, S-LAM-alpha
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P25391Laminin subunit alpha-13,0750Ensembl, GeneID, HGNC

Source UniProt

Patents67

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026515744 A2026-05-19271P25391Espacenet
JP 2026004568 A2026-01-1451081P25391Espacenet
EP 4650780 A22025-11-1910698P25391Espacenet
EP 4640849 A22025-10-291640P25391Espacenet
EP 4641201 A22025-10-2911112P25391Espacenet
JP 2025147176 A2025-10-067642P25391Espacenet
JP 2025529142 A2025-09-046849P25391Espacenet
US 12371689 B22025-07-296849P25391Espacenet
JP 2025519096 A2025-06-241640P25391Espacenet
JP 2025517969 A2025-06-1211112P25391Espacenet

1 to 10 of 67

See all 67 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
OCRIPLASMINCHEMBL2095222Laminin hydrolytic enzymeHYDROLYTIC ENZYME

Source ChEMBL

Trials10

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT02747030OCRIPLASMINPHASE1ClinicalTrials.gov
NCT02681809OCRIPLASMINPHASE22020-12-16ClinicalTrials.gov
NCT01429441OCRIPLASMINPHASE32016-01-11ClinicalTrials.gov
NCT00996684OCRIPLASMINPHASE2ClinicalTrials.gov
NCT00798317OCRIPLASMINPHASE32013-01-30ClinicalTrials.gov
NCT00781859OCRIPLASMINPHASE32013-01-28ClinicalTrials.gov
NCT00428129OCRIPLASMINPHASE2ClinicalTrials.gov
NCT00412451OCRIPLASMINPHASE22013-09-13ClinicalTrials.gov
NCT00123305OCRIPLASMINPHASE2ClinicalTrials.gov
NCT00123266OCRIPLASMINPHASE2ClinicalTrials.gov

NIH grants1,005

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleLAMA1 papersNewest fiscal year
P20GM103446Delaware INBRE52025
P30CA091842Cancer Center Support Grant32025
R01DC014461A Hydrogel-Based Cellular Model of the Human Vocal Fold32025
R01DE029655Bottom-Up Assembly of Functional Salivary Gland Tissues32025
R01EY012200Pax6 as a key regulator of lens development32025
U54GM104940Louisiana Clinical and Translational Science Center32025
P30CA008748Cancer Center Support Grant22025
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)22025
P30CA015704Cancer Center Support Grant22025
P30CA016672Cancer Center Support Grant22025

1 to 10 of 1,005Source NIH's project files

See all 1,005 nih grants

Papers1,367

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Whole-exome sequencing identifies matrisomal gene associations in monogenic cerebral small vessel disease.J Neurol202642481886PubTator, text miningPubMed
Hereditary spastic paraplegia in three siblings with distinct genetic mutations.J Int Med Res202642446524PubTator, text miningPubMed
Fostering cell-cell interactions and integrating angiocrine factors to promote the development of salivary microtissues in 3D.Bioeng Transl Med202642272969PubTator, text miningPubMed
Prenatal Diagnosis of Poretti-Boltshauser Syndrome: A Case of Live Birth with Confirmed LAMA1 Variants.Cerebellum202642105148PubTator, text miningPubMed
Novel LAMA1 Mutations in a Pedigree With Poretti-Boltshauser Syndrome: Implications for Hypomyelination.Mol Genet Genomic Med202642043906PubTator, text miningPubMed
Gene Expression Alterations Associated With Resveratrol-Induced Antiproliferative Effects and S-Phase Cell Cycle Arrest in Osteosarcoma Cancer Cells.J Cell Mol Med202641937498PubTator, text miningPubMed
Targeted proteomic and bioinformatic investigation of extracellular matrix remodeling in hAEC-EV-mediated corneal repair.Front Bioeng Biotechnol202641929428PubTator, text miningPubMed
Proteome Profiling Reveals Inflammation and Fibrosis Biomarkers in Urinary Migrasomes of Patients with Diabetic Kidney Disease.J Proteome Res202641906798PubTator, text miningPubMed
Multi-omics and causal inference reveal lactylation-based osteoblast regulatory networks and drug candidates.iScience202641736870PubTator, text miningPubMed
Small extracellular vesicles produced by homeostatic phenotype BMSC promote bone regeneration by transferring anti-senescent factor JMJD6.J Nanobiotechnology202641723429PubTator, text miningPubMed

1 to 10 of 1,367

See all 1,367 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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