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Gene · 284656

EPHA10: EPH receptor A10

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. EPHA10: EPH receptor A10. Genes, record 284656. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/284656

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Gene

Symbol
EPHA10
HGNC
Name
EPH receptor A10
HGNC
NCBI Gene ID
284656
NCBI Gene
HGNC ID
HGNC:19987
HGNC
Ensembl
ENSG00000183317
NCBI Gene
Aliases
DFNA88, FLJ16103, FLJ33655
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q5JZY3Ephrin type-A receptor 101,0080Ensembl, GeneID, HGNC

Source UniProt

Patents32

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1445075Q5JZY3Espacenet
EP 4650780 A22025-11-199226Q5JZY3Espacenet
EP 4641201 A22025-10-299462Q5JZY3Espacenet
JP 2025147176 A2025-10-064801Q5JZY3Espacenet
JP 2025529142 A2025-09-041412Q5JZY3Espacenet
JP 2025529142 A2025-09-046271Q5JZY3Espacenet
US 12371689 B22025-07-291412Q5JZY3Espacenet
US 12371689 B22025-07-296271Q5JZY3Espacenet
JP 2025517969 A2025-06-129462Q5JZY3Espacenet
JP 2025517970 A2025-06-129226Q5JZY3Espacenet

1 to 10 of 32

See all 32 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
VANDETANIBCHEMBL24828Ephrin receptor inhibitorINHIBITOR

Source ChEMBL

Trials97

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06482086VANDETANIBPHASE2ClinicalTrials.gov
NCT04211337VANDETANIBPHASE32024-06-13ClinicalTrials.gov
NCT03630120VANDETANIBPHASE22021-01-22ClinicalTrials.gov
NCT03291379VANDETANIBEARLY_PHASE12021-02-03ClinicalTrials.gov
NCT02638428VANDETANIBPHASE2ClinicalTrials.gov
NCT02530411VANDETANIBPHASE2ClinicalTrials.gov
NCT02495103VANDETANIBPHASE1/PHASE22021-01-26ClinicalTrials.gov
NCT02299999VANDETANIBPHASE2ClinicalTrials.gov
NCT02117167VANDETANIBPHASE2ClinicalTrials.gov
NCT02109250VANDETANIBClinicalTrials.gov

1 to 10 of 97

See all 97 trials

NIH grants210

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleEPHA10 papersNewest fiscal year
P30CA008748Cancer Center Support Grant62025
P30CA016672Cancer Center Support Grant52025
UL1TR001863Yale Clinical and Translational Science Award32025
I01BX002025Molecular Mechanisms of Kidney Fibrosis12025
IK6BX005240BLR&D Merit Review Research Career Scientist (RCS) Award (IK6)12025
K01AA030083Mass Multivariate Derivation and Validation of AUD Biotypes using Developmental Imaging and Genomic Approaches12025
P01DA047233Transcriptional Mechanisms of Drug Addiction12025
P30AG066512Alzheimer's Disease Research Center - Administrative Supplement 202512025
P30CA006973Regional Oncology Research Center12025
P30CA016359Cancer Center Support Grant12025

1 to 10 of 210Source NIH's project files

See all 210 nih grants

Papers352

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Modulating pseudokinase conformation from the ATP-binding site.Structure202642759518PubTator, text miningPubMed
N-Gene and T-Gene deregulation networks: a data-driven causal framework for the analysis of gene interventions in cancer.Front Syst Biol202642465838PubTator, text miningPubMed
The multifaceted roles of receptor tyrosine pseudokinases in cellular signalling.Biochem Soc Trans202642267535PubTator, text miningPubMed
Eph receptors in pancreatic cancer: Biological roles and clinical implications.Crit Rev Oncol Hematol202641903913PubTator, text miningPubMed
Distinct molecular pathways leading to dosage-dependent temozolomide resistance in GBM stem cells.Cancer Cell Int202641736030PubTator, text miningPubMed
FOXM1 regulates platelet-induced anoikis resistance in pancreatic cancer cells.Cell Commun Signal202641535944PubTator, text miningPubMed
Targeting ephrin receptor A10 with antibody-drug conjugates for breast cancer.Cancer Lett202641423054PubTator, text miningPubMed
The N6-methyladenosine Modified EphA10 Promotes Prostate Cancer Progression by Activating the ERK/AKT Pathway.Biochem Genet202641296142PubTator, text miningPubMed
Elevated Expression of EphA10 in Gastric Cancer Tissues: A Potential Biomarker for Tumor Metastasis and Poor Survival.Tohoku J Exp Med202640603106PubTator, text miningPubMed
A new serological autoantibody signature associated with multiple sclerosis.Neurobiol Dis202541038542PubTator, text miningPubMed

1 to 10 of 352

See all 352 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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