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Gene · 28514

DLL1: delta like canonical Notch ligand 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. DLL1: delta like canonical Notch ligand 1. Genes, record 28514. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/28514

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Gene

Symbol
DLL1
HGNC
Name
delta like canonical Notch ligand 1
HGNC
NCBI Gene ID
28514
NCBI Gene
HGNC ID
HGNC:2908
HGNC
Ensembl
ENSG00000198719
NCBI Gene
Aliases
DELTA1, DL1, Delta, NEDBAS
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O00548Delta-like protein 17231Ensembl, GeneID, HGNC

Source UniProt

Patents307

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4830720 A12026-10-285O00548Espacenet
EP 4781198 A12026-07-291O00548Espacenet
EP 4756030 A12026-06-1020O00548Espacenet
JP 2026508154 A2026-03-105O00548Espacenet
US 12570741 B22026-03-1018O00548Espacenet
EP 4650780 A22025-11-198106O00548Espacenet
WO 2025228986 A12025-11-0623O00548Espacenet
EP 4644537 A12025-11-0523O00548Espacenet
EP 4641201 A22025-10-298247O00548Espacenet
KR 1020250153805 A2025-10-275O00548Espacenet

1 to 10 of 307

See all 307 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,453

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleDLL1 papersNewest fiscal year
P30CA016672Cancer Center Support Grant202025
P30CA008748Cancer Center Support Grant192025
R01AI091627Notch Signaling in Alloimmunity122025
R24HD000836Laboratory of Developmental Biology82025
P30CA016058Cancer Center Support Grant72025
P30CA016087Cancer Center Support Grant72025
P30CA013330Cancer Center Support Grant52025
P30CA016042Cancer Center Support Grant52025
P01CA065493Off-the-Shelf Immune Effector Cells for Hematological Malignancies42025
P30CA016056Roswell Park Cancer Center Support Grant42025

1 to 10 of 2,453Source NIH's project files

See all 2,453 nih grants

Papers3,332

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Pan-cancer analysis of Notch pathway-linked gene expression identifies tumour-specific and sex-stratified prognostic associations.Clin Transl Radiat Oncol202642668613PubTator, text miningPubMed
The causal role of plasma protein ratios in ulcerative colitis: insights from mendelian randomization and single-cell sequencing.Open Med (Wars)202642577736PubTator, text miningPubMed
The Mechanism of Icariin in Regulating BMSCs for Treating Osteoporosis: A Review.Endocr Metab Immune Disord Drug Targets202642576520PubTator, text miningPubMed
PTPN14 functions as an oncogenic promoter in colon adenocarcinoma and liver hepatocellular carcinoma via Notch Signaling.Cell Signal202642501829PubTator, text miningPubMed
Molecular Pathogenesis and Therapeutic Response of Diffuse Large B Cell Lymphoma Genetic Subtypes.Annu Rev Cancer Biol202642487683PubTator, text miningPubMed
DLL1-mediated ferroptosis resistance via the Notch-Nrf2/GPX4 axis drives cisplatin resistance in ovarian cancer.Cancer Metab202642310697PubTator, text miningPubMed
Evaluating the diagnostic and prognostic utility of serum DLL1 in acute-on-chronic liver failure patients with bacterial infections.Front Med (Lausanne)202642221134PubTator, text miningPubMed
Novel NOTCH1-unmutated T-ALL Cell Line With Suppressed Growth by Gamma-secretase Inhibitors.Anticancer Res202642203317PubTator, text miningPubMed
Type 1 Diabetes and Multiple Sclerosis Share General Autoimmunity Genetic Variation.Genes (Basel)202642194988PubTator, text miningPubMed
Trio Whole-Genome Sequencing for Diagnosis of Neonates with Multiple Congenital Anomalies.Neonatology202642139173PubTator, text miningPubMed

1 to 10 of 3,332

See all 3,332 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/28514

GET https://conductscience.org/api/genes/v1/28514/patents?page=2