Gene · 28514
DLL1: delta like canonical Notch ligand 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. DLL1: delta like canonical Notch ligand 1. Genes, record 28514. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/28514
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O00548 | Delta-like protein 1 | 723 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents307
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4830720 A1 | 2026-10-28 | 5 | O00548 | Espacenet |
| EP 4781198 A1 | 2026-07-29 | 1 | O00548 | Espacenet |
| EP 4756030 A1 | 2026-06-10 | 20 | O00548 | Espacenet |
| JP 2026508154 A | 2026-03-10 | 5 | O00548 | Espacenet |
| US 12570741 B2 | 2026-03-10 | 18 | O00548 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 8106 | O00548 | Espacenet |
| WO 2025228986 A1 | 2025-11-06 | 23 | O00548 | Espacenet |
| EP 4644537 A1 | 2025-11-05 | 23 | O00548 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 8247 | O00548 | Espacenet |
| KR 1020250153805 A | 2025-10-27 | 5 | O00548 | Espacenet |
1 to 10 of 307
See all 307 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,453
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | DLL1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 20 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 19 | 2025 |
| R01AI091627 | Notch Signaling in Alloimmunity | 12 | 2025 |
| R24HD000836 | Laboratory of Developmental Biology | 8 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 7 | 2025 |
| P30CA016087 | Cancer Center Support Grant | 7 | 2025 |
| P30CA013330 | Cancer Center Support Grant | 5 | 2025 |
| P30CA016042 | Cancer Center Support Grant | 5 | 2025 |
| P01CA065493 | Off-the-Shelf Immune Effector Cells for Hematological Malignancies | 4 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 4 | 2025 |
1 to 10 of 2,453Source NIH's project files
See all 2,453 nih grantsPapers3,332
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Pan-cancer analysis of Notch pathway-linked gene expression identifies tumour-specific and sex-stratified prognostic associations. | Clin Transl Radiat Oncol | 2026 | 42668613 | PubTator, text mining | PubMed |
| The causal role of plasma protein ratios in ulcerative colitis: insights from mendelian randomization and single-cell sequencing. | Open Med (Wars) | 2026 | 42577736 | PubTator, text mining | PubMed |
| The Mechanism of Icariin in Regulating BMSCs for Treating Osteoporosis: A Review. | Endocr Metab Immune Disord Drug Targets | 2026 | 42576520 | PubTator, text mining | PubMed |
| PTPN14 functions as an oncogenic promoter in colon adenocarcinoma and liver hepatocellular carcinoma via Notch Signaling. | Cell Signal | 2026 | 42501829 | PubTator, text mining | PubMed |
| Molecular Pathogenesis and Therapeutic Response of Diffuse Large B Cell Lymphoma Genetic Subtypes. | Annu Rev Cancer Biol | 2026 | 42487683 | PubTator, text mining | PubMed |
| DLL1-mediated ferroptosis resistance via the Notch-Nrf2/GPX4 axis drives cisplatin resistance in ovarian cancer. | Cancer Metab | 2026 | 42310697 | PubTator, text mining | PubMed |
| Evaluating the diagnostic and prognostic utility of serum DLL1 in acute-on-chronic liver failure patients with bacterial infections. | Front Med (Lausanne) | 2026 | 42221134 | PubTator, text mining | PubMed |
| Novel NOTCH1-unmutated T-ALL Cell Line With Suppressed Growth by Gamma-secretase Inhibitors. | Anticancer Res | 2026 | 42203317 | PubTator, text mining | PubMed |
| Type 1 Diabetes and Multiple Sclerosis Share General Autoimmunity Genetic Variation. | Genes (Basel) | 2026 | 42194988 | PubTator, text mining | PubMed |
| Trio Whole-Genome Sequencing for Diagnosis of Neonates with Multiple Congenital Anomalies. | Neonatology | 2026 | 42139173 | PubTator, text mining | PubMed |
1 to 10 of 3,332
See all 3,332 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/28514
GET https://conductscience.org/api/genes/v1/28514/patents?page=2