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Gene · 2852

GPER1: G protein-coupled estrogen receptor 1

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. GPER1: G protein-coupled estrogen receptor 1. Genes, record 2852. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/2852

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
GPER1
HGNC
Name
G protein-coupled estrogen receptor 1
HGNC
NCBI Gene ID
2852
NCBI Gene
HGNC ID
HGNC:4485
HGNC
Ensembl
ENSG00000164850
NCBI Gene
Aliases
CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPER, GPR30, LERGU, LERGU2, LyGPR, mER
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q99527G protein-coupled estrogen receptor 13755Ensembl, GeneID, HGNC

Source UniProt

Patents98

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1446950Q99527Espacenet
JP 2026004568 A2026-01-1446952Q99527Espacenet
JP 2026004568 A2026-01-1446953Q99527Espacenet
JP 2026004568 A2026-01-1446954Q99527Espacenet
EP 4640849 A22025-10-29493Q99527Espacenet
EP 4641201 A22025-10-293390Q99527Espacenet
JP 2025147176 A2025-10-066138Q99527Espacenet
JP 2025147176 A2025-10-066139Q99527Espacenet
JP 2025147176 A2025-10-066140Q99527Espacenet
JP 2025147176 A2025-10-066141Q99527Espacenet

1 to 10 of 98

See all 98 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,925

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30CA118100University of New Mexico Cancer Center Support Grant402025
R01CA194496Molecular Mechanisms and Applications of Novel ER/GPER-selective Ligands212025
R01DK074970Genetic and molecular architecture of sex-specific drug response in human islets152025
P20GM121176Autophagy, Inflammation and Metabolism (AIM) in Disease Center - Phase 2.142025
P01AG026572Perimenopause in Brain Aging and Alzheimer's Disease72025
ZIAES021196Pathobiology Of Uterine Leiomyomas (fibroids)72025
P30CA051008Georgetown University Lombardi Comprehensive Cancer Center Support Grant62025
P30ES017885Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD)62025
T32HL007736Minority Institutional Research Training Program (T32)62025
P20GM103430Rhode Island IDeA Network of Biomedical Research Excellence52025

1 to 10 of 1,925Source NIH's project files

See all 1,925 nih grants

Papers4,367

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818121PubTator, text miningPubMed
42811967PubTator, text miningPubMed
42811636PubTator, text miningPubMed
42800332PubTator, text miningPubMed
42768448PubTator, text miningPubMed
42763886PubTator, text miningPubMed
42748840PubTator, text miningPubMed
42737662PubTator, text miningPubMed
42735289PubTator, text miningPubMed
42717828PubTator, text miningPubMed

1 to 10 of 4,367

See all 4,367 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2852

GET https://conductscience.org/api/genes/v1/2852/patents?page=2