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Gene · 285220

EPHA6: EPH receptor A6

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. EPHA6: EPH receptor A6. Genes, record 285220. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/285220

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Gene

Symbol
EPHA6
HGNC
Name
EPH receptor A6
HGNC
NCBI Gene ID
285220
NCBI Gene
HGNC ID
HGNC:19296
HGNC
Ensembl
ENSG00000080224
NCBI Gene
Aliases
EHK-2, EHK2, EK12, EPA6, FLJ35246, HEK12, PRO57066
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9UF33Ephrin type-A receptor 61,0360Ensembl, GeneID, HGNC

Source UniProt

Patents31

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2025529142 A2025-09-041417Q9UF33Espacenet
US 12371689 B22025-07-291417Q9UF33Espacenet
JP 2024514157 A2024-03-28217Q9UF33Espacenet
KR 1020240007143 A2024-01-16217Q9UF33Espacenet
WO 2020043864 A12020-03-05803Q9UF33Espacenet
US 7795412 B22010-09-14104Q9UF33Espacenet
JP 2010527589 A2010-08-198Q9UF33Espacenet
US 7589172 A2009-09-15104Q9UF33Espacenet
US 7582293 A2009-09-01104Q9UF33Espacenet
JP 2009527227 A2009-07-30171Q9UF33Espacenet

1 to 10 of 31

See all 31 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
VANDETANIBCHEMBL24828Ephrin receptor inhibitorINHIBITOR

Source ChEMBL

Trials97

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06482086VANDETANIBPHASE2ClinicalTrials.gov
NCT04211337VANDETANIBPHASE32024-06-13ClinicalTrials.gov
NCT03630120VANDETANIBPHASE22021-01-22ClinicalTrials.gov
NCT03291379VANDETANIBEARLY_PHASE12021-02-03ClinicalTrials.gov
NCT02638428VANDETANIBPHASE2ClinicalTrials.gov
NCT02530411VANDETANIBPHASE2ClinicalTrials.gov
NCT02495103VANDETANIBPHASE1/PHASE22021-01-26ClinicalTrials.gov
NCT02299999VANDETANIBPHASE2ClinicalTrials.gov
NCT02117167VANDETANIBPHASE2ClinicalTrials.gov
NCT02109250VANDETANIBClinicalTrials.gov

1 to 10 of 97

See all 97 trials

NIH grants447

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleEPHA6 papersNewest fiscal year
P30CA008748Cancer Center Support Grant72025
P30CA016672Cancer Center Support Grant52025
P30AG062715Wisconsin Alzheimer's Disease Research Center22025
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)22025
P30CA016520Abramson Cancer Center Support Grant22025
P30CA046934University of Colorado Cancer Center Support Grant22025
P30CA069533OHSU Knight Cancer Institute22025
P30ES023513UC Davis Environmental Health Sciences Core Center22025
R01AG072758Maladaptive antiviral pathways in Alzheimer's disease22025
R01AG074541cGAS inhibitors for Alzheimer's disease treatment22025

1 to 10 of 447Source NIH's project files

See all 447 nih grants

Papers448

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Weighted Single-Step Genomic Evaluation of Body Structural Traits for Early Selection of Growth Performance in Thai Swamp Buffalo.Animals (Basel)202642450718PubTator, text miningPubMed
Machine Learning-Based Prediction of Masaoka-Koga Stage and WHO Histological Risk Group in Thymic Epithelial Tumors Using Biomarker Combinations.Diagnostics (Basel)202642449899PubTator, text miningPubMed
Identification of telomere-related genes in the progression of colon adenocarcinoma: a bioinformatics analysis.J Gastrointest Oncol202642434232PubTator, text miningPubMed
Mathematical Modeling of Human Retinal Vascular Pattern Around the Foveal Avascular Zone.Transl Vis Sci Technol202641769944PubTator, text miningPubMed
Bridging cancer cell-intrinsic driver genes and -extrinsic cell-cell communication with Driver2Comm.PLoS Comput Biol202641701761PubTator, text miningPubMed
FOXM1 regulates platelet-induced anoikis resistance in pancreatic cancer cells.Cell Commun Signal202641535944PubTator, text miningPubMed
From thought to action: The organization of spinal projecting neurons.Cell Rep202540818073PubTator, text miningPubMed
Mef2c Controls Postnatal Callosal Axon Targeting by Regulating Sensitivity to Ephrin Repulsion.J Neurosci202540228894PubTator, text miningPubMed
Illuminating the dark kinome: utilizing multiplex peptide activity arrays to functionally annotate understudied kinases.Cell Commun Signal202439415254PubTator, text miningPubMed
[Clinicopathological analysis of gastric adenocarcinoma with elevated serum alpha-fetoprotein and enteroblastic differentiation].Zhonghua Zhong Liu Za Zhi202439034804PubTator, text miningPubMed

1 to 10 of 448

See all 448 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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