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Gene · 285335

SLC9C1: solute carrier family 9 member C1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SLC9C1: solute carrier family 9 member C1. Genes, record 285335. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/285335

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Gene

Symbol
SLC9C1
HGNC
Name
solute carrier family 9 member C1
HGNC
NCBI Gene ID
285335
NCBI Gene
HGNC ID
HGNC:31401
HGNC
Ensembl
ENSG00000172139
NCBI Gene
Aliases
NHE, NHE-10, SLC9A10, sperm-NHE
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q4G0N8Solute carrier family 9 member C11,1771Ensembl, GeneID, HGNC

Source UniProt

Patents15

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1464886Q4G0N8Espacenet
EP 4641201 A22025-10-293979Q4G0N8Espacenet
JP 2025529142 A2025-09-044323Q4G0N8Espacenet
US 12371689 B22025-07-294323Q4G0N8Espacenet
JP 2025517969 A2025-06-123979Q4G0N8Espacenet
US 11446398 B22022-09-2082266Q4G0N8Espacenet
JP 2022524081 A2022-04-27185237Q4G0N8Espacenet
US 11078247 B22021-08-0310621Q4G0N8Espacenet
JP 2019054813 A2019-04-11245321Q4G0N8Espacenet
JP 2017121241 A2017-07-13245321Q4G0N8Espacenet

1 to 10 of 15

See all 15 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants839

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSLC9C1 papersNewest fiscal year
P30DK042086Center for Interdisciplinary Study of Inflammatory Intestinal DIsorders (C-IID)72025
R01NS048216Na/H Exchanger in Microglial Metabolism and Function72025
P30CA062203Cancer Center Support Grant32025
P30DK036836Diabetes Research Center32025
R01CA207189Regulation of Nutrient Stress-Induced Macropinocytosis in Pancreatic Ductal Adenocarcinoma32025
R01HL071158Acid, Succinate and Glyoxal Metabolism in Ischemia32025
P30CA016042Cancer Center Support Grant22025
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant22025
P30CA030199Cancer Center Support Grant (CCSG)22025
P30CA068485Cancer Center Support Grant22025

1 to 10 of 839Source NIH's project files

See all 839 nih grants

Papers1,657

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
SGLT2-Inhibitors and Molecular Signatures of Aortic Valve Remodeling in Severe Aortic Stenosis: The Valve-AS Study.JACC Basic Transl Sci202642663337PubTator, text miningPubMed
NHE1-Mediated Metabolic Reprogramming in Cancer.Metabolites202641893344PubTator, text miningPubMed
pH-regulating Lipiodol Pickering emulsions enhance transarterial embolization therapy via inducing ferroptosis and activating antitumor immunity.Cell Rep Med202641850231PubTator, text miningPubMed
The Role of Renal Na+/H+ Exchange in the Regulation of Acid-Base and Sodium Homeostasis in Premature Infants.Physiol Res202641811697PubTator, text miningPubMed
Calcineurin Homologous Protein 2 Acts as a Conditional Modulator of Migration and Proliferation in Human Bone Sarcoma Cells.Cancers (Basel)202641749826PubTator, text miningPubMed
Dual Role of the Endometrial Microbiome-Immune Axis: From Endometrial Homeostasis to Reproductive Disorders.Int J Womens Health202641710143PubTator, text miningPubMed
Lactate transmission from hypoxic tumor cells promotes macrophage senescence and M2 polarization via the DNMT1-NHE7 axis to accelerate endometrial cancer progression.Cell Death Dis202641617670PubTator, text miningPubMed
Soluble adenylyl cyclase in nonmammalian sperm is directly controlled by pH, not by HCO3- or Ca2.Proc Natl Acad Sci U S A202641591904PubTator, text miningPubMed
Advancements in early biomarkers of acute kidney injury: from traditional indicators to a paradigm shift in lactate metabolism.Ann Med202641530927PubTator, text miningPubMed
The pH perspective of cancer: From warburg's misconception to therapeutic targeting of pH regulating proteins.Crit Rev Oncol Hematol202641309010PubTator, text miningPubMed

1 to 10 of 1,657

See all 1,657 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/285335

GET https://conductscience.org/api/genes/v1/285335/patents