ConductScience.org, home

Gene · 286

ANK1: ankyrin 1

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. ANK1: ankyrin 1. Genes, record 286. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/286

On this page

Gene

Symbol
ANK1
HGNC
Name
ankyrin 1
HGNC
NCBI Gene ID
286
NCBI Gene
HGNC ID
HGNC:492
HGNC
Ensembl
ENSG00000029534
NCBI Gene
Aliases
ANK, SPH1, SPH2, ankyrin-1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P16157Ankyrin-11,88121Ensembl, GeneID, HGNC

Source UniProt

Patents30

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1437409P16157Espacenet
EP 4641201 A22025-10-296202P16157Espacenet
JP 2025147176 A2025-10-06835P16157Espacenet
JP 2025529142 A2025-09-045485P16157Espacenet
US 12371689 B22025-07-295485P16157Espacenet
JP 2025517969 A2025-06-126202P16157Espacenet
JP 2025062604 A2025-04-144853P16157Espacenet
JP 2025028160 A2025-02-28835P16157Espacenet
KR 1020250010750 A2025-01-21835P16157Espacenet
JP 2024109657 A2024-08-14842P16157Espacenet

1 to 10 of 30

See all 30 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,147

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleANK1 papersNewest fiscal year
R01DK093757Genetic epidemiology of rare and regulatory variants for metabolic traits102025
ZIABC007365Regulation of ADP-ribosylation factor102025
R01DK062370Identifying Genes for Type 2 Diabetes: FUSION72025
P30CA008748Cancer Center Support Grant62025
P30DK020572Michigan Diabetes Research Center (MDRC)62025
P30CA016058Cancer Center Support Grant52025
R01HL086694From GWAS loci to blood pressure genes, variants & mechanisms - Renewal52025
T32AR007592Interdisciplinary Training Program in Muscle Biology52025
UL1TR001863Yale Clinical and Translational Science Award52025
ZIAHG000024Genetic analysis of type II diabetes52025

1 to 10 of 2,147Source NIH's project files

See all 2,147 nih grants

Papers2,731

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Identification of a shared blood-brain transcriptomic signature in Parkinson's disease using bioinformatic and network pharmacology approaches.Neuroscience202642826760PubTator, text miningPubMed
Clinical characteristics, genotype-phenotype correlation, and prognostic follow-up of 48 Chinese children with hereditary spherocytosis.Front Med (Lausanne)202642819045PubTator, text miningPubMed
Molecular Distinctions, Diagnosis, and Mechanism-Based Therapies in Lipedema and Obesity.Curr Issues Mol Biol202642793248PubTator, text miningPubMed
Capsaicin and cinnamaldehyde as topical transient receptor potential vanilloid 1 and transient receptor potential ankyrin 1 agonists in humans: Formulation, stability, and pharmacodynamic evaluation.J Pharmacol Exp Ther202642772018PubTator, text miningPubMed
Regulation of transient receptor potential ankyrin-1 agonist-induced airway epithelial cell injury and repair by protein kinase C and p38 mitogen-activated kinase.Mol Pharmacol202642759295PubTator, text miningPubMed
Pharmacological readthrough and base editing for ANK1 nonsense mutations in an erythroid model of hereditary spherocytosis.Mol Ther Nucleic Acids202642667096PubTator, text miningPubMed
miR-486-5p suppresses autophagy in hepatocellular carcinoma via activation of the AKT/mTOR signalling pathway.Mol Biomed202642635933PubTator, text miningPubMed
Novel 1,3,5-triazine-based TRPA1 activators alleviate pro-fibrotic response in human lung fibroblasts.Eur J Pharmacol202642601007PubTator, text miningPubMed
Alzheimer's Disease DNA Methylation Index (AD-DMI) and its Association with Late-Life Cognitive Function.NPJ Dement202642583477PubTator, text miningPubMed
Case Report: A research on a case of hereditary spherocytosis with idiopathic pulmonary hemosiderosis.Front Pediatr202642558654PubTator, text miningPubMed

1 to 10 of 2,731

See all 2,731 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/286

GET https://conductscience.org/api/genes/v1/286/patents?page=2