Gene · 2864
FFAR1: free fatty acid receptor 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. FFAR1: free fatty acid receptor 1. Genes, record 2864. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2864
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O14842 | Free fatty acid receptor 1 | 300 | 9 | Ensembl, GeneID, HGNC |
Source UniProt
Patents50
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2025529142 A | 2025-09-04 | 1566 | O14842 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1566 | O14842 | Espacenet |
| EP 4514831 A1 | 2025-03-05 | 3 | O14842 | Espacenet |
| US 11583528 B2 | 2023-02-21 | 34 | O14842 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 32886 | O14842 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 3269 | O14842 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 135857 | O14842 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 3998 | O14842 | Espacenet |
| US 10772934 B2 | 2020-09-15 | 1072 | O14842 | Espacenet |
| US 10668104 B2 | 2020-06-02 | 13 | O14842 | Espacenet |
1 to 10 of 50
See all 50 patentsDrugs3
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
Trials24
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT03184584 | SETOGEPRAM | PHASE2/PHASE3 | ClinicalTrials.gov | |
| NCT03081598 | SETOGEPRAM | PHASE2 | ClinicalTrials.gov | |
| NCT02955888 | SETOGEPRAM | PHASE2 | ClinicalTrials.gov | |
| NCT02739217 | SETOGEPRAM | PHASE2 | ClinicalTrials.gov | |
| NCT02562573 | SETOGEPRAM | PHASE2 | ClinicalTrials.gov | |
| NCT02538536 | SETOGEPRAM | PHASE2 | ClinicalTrials.gov | |
| NCT02015780 | FASIGLIFAM | PHASE3 | ClinicalTrials.gov | |
| NCT01982253 | FASIGLIFAM | PHASE2 | 2016-10-07 | ClinicalTrials.gov |
| NCT01834274 | FASIGLIFAM | PHASE3 | 2015-09-28 | ClinicalTrials.gov |
| NCT01829477 | FASIGLIFAM | PHASE3 | 2016-06-01 | ClinicalTrials.gov |
1 to 10 of 24
See all 24 trialsNIH grants608
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | FFAR1 papers | Newest fiscal year |
|---|---|---|---|
| P30DK063491 | Diabetes Research Center (DRC) | 4 | 2025 |
| R35GM128641 | Structure, pharmacology and signaling of G protein-coupled receptors (GPCRs) in inflammation | 4 | 2025 |
| P30DK056341 | Washington University Nutrition Obesity Research Center | 3 | 2025 |
| R01EY017017 | Dietary control of angiogenesis in retinopathy models | 3 | 2025 |
| P01HL151328 | Triglycerides, Diabetes and Cardiovascular Disease | 2 | 2025 |
| P30DK020572 | Michigan Diabetes Research Center (MDRC) | 2 | 2025 |
| P30DK020593 | Vanderbilt Diabetes Research Center | 2 | 2025 |
| P30DK034854 | Integrated Epithelial and Muscosal Biology | 2 | 2025 |
| P30DK043351 | Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital | 2 | 2025 |
| P30DK058404 | Molecular and Cellular Basis for Digestive Diseases | 2 | 2025 |
1 to 10 of 608Source NIH's project files
See all 608 nih grantsPapers1,574
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Decoding dietary fat: molecular sensing, brain integration, and the biology of flavor. | Can J Physiol Pharmacol | 2026 | 42826400 | PubTator, text mining | PubMed |
| Molecular mechanisms of lipid sensing in human cholecystokinin-secreting enteroendocrine cells. | Mol Metab | 2026 | 42805486 | PubTator, text mining | PubMed |
| Sphinganine as a novel stimulator of GLP-1 secretion. | Diabetologia | 2026 | 42782508 | PubTator, text mining | PubMed |
| Effects of Fluoride and 8:2 FTOH on β-Cell Calcium Signaling and Insulin Homeostasis: An Exploratory Study. | Metabolites | 2026 | 42506423 | PubTator, text mining | PubMed |
| Synthesis and structure-activity relationship evaluation of hypoglycemic activity of novel borneol and isoborneol containing (hydroxyphenyl)propanoic acids as FFAR1 agonists. | Med Chem Res | 2026 | 42446660 | PubTator, text mining | PubMed |
| Maternal obesity induces macrophage to myofibroblast transition in kidneys of male offspring through a pathway driven by 20-hydroxyeicosatetraenoic acid. | Nat Commun | 2026 | 42135322 | PubTator, text mining | PubMed |
| Revisiting GPR40 Agonist in Type 2 Diabetes Mellitus: A Cautious but Meaningful Return. | Diabetes Metab J | 2026 | 42128401 | PubTator, text mining | PubMed |
| The Ca2+-NO-ROS Crosstalk Induced by Arachidonic Acid in Human Lung Fibroblasts: Implications for Pulmonary Fibrosis. | Int J Mol Sci | 2026 | 42123594 | PubTator, text mining | PubMed |
| The roles of free-fatty acid receptors in the pathophysiology of renal disorders. | J Pharmacol Exp Ther | 2026 | 42096898 | PubTator, text mining | PubMed |
| Short-, medium-, versus long-chain fatty acids: mechanisms of immunomodulation and disease pathogenesis. | Cell Mol Immunol | 2026 | 42056219 | PubTator, text mining | PubMed |
1 to 10 of 1,574
See all 1,574 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2864
GET https://conductscience.org/api/genes/v1/2864/patents?page=2