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Gene · 2865

FFAR3: free fatty acid receptor 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FFAR3: free fatty acid receptor 3. Genes, record 2865. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2865

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Gene

Symbol
FFAR3
HGNC
Name
free fatty acid receptor 3
HGNC
NCBI Gene ID
2865
NCBI Gene
HGNC ID
HGNC:4499
HGNC
Ensembl
ENSG00000185897
NCBI Gene
Aliases
FFA3R, GPR41
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O14843Free fatty acid receptor 33462Ensembl, GeneID, HGNC

Source UniProt

Patents31

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2025529142 A2025-09-041568O14843Espacenet
US 12371689 B22025-07-291568O14843Espacenet
US 11446398 B22022-09-2032889O14843Espacenet
US 11446398 B22022-09-2032890O14843Espacenet
JP 2022524081 A2022-04-27135860O14843Espacenet
JP 2022524081 A2022-04-27135861O14843Espacenet
US 11078247 B22021-08-034000O14843Espacenet
US 10772934 B22020-09-151073O14843Espacenet
US 10292374 B22019-05-21502O14843Espacenet
US 9782454 B22017-10-101073O14843Espacenet

1 to 10 of 31

See all 31 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants737

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFFAR3 papersNewest fiscal year
R01HL132448Antihypertensive Mechanisms of Minocycline in Resistant Hypertension: Role of the gut microbiota-brain-immune axis42025
U19AI070235Epithelial Genes in Allergic Inflammation42025
UL1TR001863Yale Clinical and Translational Science Award42025
P30DK040561Boston Area Nutrition Obesity Research Center (NORC)32025
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital32025
P30DK063491Diabetes Research Center (DRC)32025
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease32025
P30ES010126UNC Center for Environmental Health and Susceptibility32025
R01AI124355Genetic and Immunological Dissection of Eosinophilic Esophagitis32025
D43TW009744UNZA-Vanderbilt Training Partnership for HIV-NCD Research (UVP-2)22025

1 to 10 of 737Source NIH's project files

See all 737 nih grants

Papers2,060

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Butyrate triggers neuronal signaling via release of colonic serotonin in a microfluidic model of gut-brain axis.Am J Physiol Gastrointest Liver Physiol202642814738PubTator, text miningPubMed
Short-Chain Fatty Acids in Sepsis: Mechanisms of Action and Therapeutic Advances.Biomedicines202642792734PubTator, text miningPubMed
Gut microbiota modulates nonalcoholic fatty liver disease (NAFLD) progression via regulation of gluconeogenesis: mechanisms and translational research.Pharmacol Res202642749095PubTator, text miningPubMed
Dietary plant polysaccharides as modulators of brain aging: mechanistic links to inflammaging, the gut brain axis and amyloid tau pathology.Nutr Neurosci202642530981PubTator, text miningPubMed
Gut-Brain Axis Mechanisms and Microbiome Abnormalities in Autism Spectrum Disorder and Therapeutic Implications.Curr Neuropharmacol202642458949PubTator, text miningPubMed
Microbiota-dependent biotransformation of apiin drives butyrate-associated protection against colitis.NPJ Sci Food202642448689PubTator, text miningPubMed
Interactions between nutrition, GLP-1 secretion, and composition of the gut microbiome.Curr Opin Clin Nutr Metab Care202642165244PubTator, text miningPubMed
Acidosis enables the NLRP3 inflammasome-inhibiting effects of β-hydroxybutyrate and short-chain carboxylic acids.J Immunol202642153447PubTator, text miningPubMed
The roles of free-fatty acid receptors in the pathophysiology of renal disorders.J Pharmacol Exp Ther202642096898PubTator, text miningPubMed
Gut microbiota-mediated metabolic dysregulation in type 2 diabetes and metabolic syndrome: emerging therapeutic targets beyond glycaemic control.Diabetes Res Clin Pract202642086084PubTator, text miningPubMed

1 to 10 of 2,060

See all 2,060 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2865

GET https://conductscience.org/api/genes/v1/2865/patents?page=2