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Gene · 287

ANK2: ankyrin 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ANK2: ankyrin 2. Genes, record 287. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/287

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Gene

Symbol
ANK2
HGNC
Name
ankyrin 2
HGNC
NCBI Gene ID
287
NCBI Gene
HGNC ID
HGNC:493
HGNC
Ensembl
ENSG00000145362
NCBI Gene
Aliases
ANK-2, CFAP87, FAP87, LQT4, brank-2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q01484Ankyrin-23,95711Ensembl, GeneID, HGNC

Source UniProt

Patents19

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1437419Q01484Espacenet
EP 4641201 A22025-10-297329Q01484Espacenet
JP 2025517969 A2025-06-127329Q01484Espacenet
JP 2025062604 A2025-04-144859Q01484Espacenet
JP 2022141755 A2022-09-29224Q01484Espacenet
US 11446398 B22022-09-204859Q01484Espacenet
JP 2022524081 A2022-04-27107830Q01484Espacenet
JP 2019054813 A2019-04-11217854Q01484Espacenet
JP 2017121241 A2017-07-13217854Q01484Espacenet
JP 2016519285 A2016-06-30224Q01484Espacenet

1 to 10 of 19

See all 19 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,548

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleANK2 papersNewest fiscal year
R01MH107182Postsynaptic roles of ankyrins62025
P30EY005722Center Core Grant for Vision Research42025
P30EY010572Ophthalmology Core Facility42025
R01HL092577IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL42025
R01HL131517Sex-specific arrhythmogenic mechanisms of atrial fibrillation42025
R01MH101221Rare Mutations and Autism Spectrum Disorders42025
T32HG002295Training in Bioinformatics and Integrative Genomics42025
P30CA008748Cancer Center Support Grant32025
P30CA016086Cancer Center Support Grant32025
P30CA016359Cancer Center Support Grant32025

1 to 10 of 1,548Source NIH's project files

See all 1,548 nih grants

Papers1,566

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Longitudinal Characterization of Giant ANK2-Depleted Monkeys Suggests Neurodevelopmental-Disorder-Like Phenotypes.Research (Wash D C)202642707610PubTator, text miningPubMed
Prenatal diagnosis of a familial 4q26 duplication encompassing the genes of ANK2, MYOZ2 and USP53 associated with asymptomatic carrier members in the family.Taiwan J Obstet Gynecol202642642122PubTator, text miningPubMed
Molecular determinants of functional voltage-gated sodium (Nav) channel diversity in mammalian central neurons.J Physiol202642555659PubTator, text miningPubMed
High-degree atrioventricular block in a child with an ANK2 variant and long QT phenotype requiring leadless pacemaker implantation.Cardiol Young202642493853PubTator, text miningPubMed
Subcortical Dendritic Scaffolding in Autism Spectrum Disorder: A Testable ANK2-SCN2A-SHANK Framework.Int J Mol Sci202642450246PubTator, text miningPubMed
Epigenetic regulation of cardiac physiology and pathophysiology: biological sex matters.J Cardiovasc Aging202642369572PubTator, text miningPubMed
A human corticospinal organoid-slice connectoid model informs enhancer strategies for post-injury axon regrowth.Cell Rep202642201810PubTator, text miningPubMed
Comprehensive Pathologic and Genetic Investigation of Four Young Adults with a Short QT Interval and Sudden Unexpected Death.J Mol Diagn202642092729PubTator, text miningPubMed
Metabolic-Epigenetic Crosstalk in Takayasu Arteritis: The ANK2-MAVS-IL-8 Axis as a Novel Therapeutic Paradigm.Int J Mol Sci202641977430PubTator, text miningPubMed
miR-4260 serves as a prognostic biomarker and suppresses thyroid cancer progression.Endokrynol Pol202641972507PubTator, text miningPubMed

1 to 10 of 1,566

See all 1,566 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/287

GET https://conductscience.org/api/genes/v1/287/patents