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GPT: glutamic--pyruvic transaminase

1 protein, 44 patents, 0 drugs, 0 trials, 8,705 NIH grants and 66,115 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolGPTHGNC
Nameglutamic--pyruvic transaminaseHGNC
NCBI Gene ID2875NCBI Gene
HGNC IDHGNC:4552HGNC
EnsemblENSG00000167701NCBI Gene
AliasesAAT1, ALT, ALT1, GPT-1, GPT1, SGPTNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P24298Alanine aminotransferase 14960Ensembl, GeneID, HGNCUniProt

Patents 44

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1447839P24298Espacenet
JP 2026004568 A2026-01-1447840P24298Espacenet
EP 4641201 A22025-10-2911679P24298Espacenet
JP 2025517969 A2025-06-1211679P24298Espacenet
JP 2024520411 A2024-05-2414P24298Espacenet
KR 1020240025536 A2024-02-277P24298Espacenet
US 11446398 B22022-09-2035165P24298Espacenet
US 11446398 B22022-09-2035166P24298Espacenet
JP 2022524081 A2022-04-27138136P24298Espacenet
JP 2022524081 A2022-04-27138137P24298Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 8705

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant1382,025NIH's project files
P30CA016672Cancer Center Support Grant1332,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award912,025NIH's project files
U01DK061734Clinical Research on Nonalcoholic Fatty Liver Disease882,025NIH's project files
P30DK026743UCSF Liver Center712,025NIH's project files
U01DK061732Continuation of the Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) Clinical Center-Cleveland site692,025NIH's project files
P30DK120515San Diego Digestive Diseases Research Center662,025NIH's project files
U01DK061737Collaborative Clinical Research in Nonalcoholic Steatohepatitis622,025NIH's project files
U01DK061738Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN)602,025NIH's project files
U01DK061713Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN)592,025NIH's project files

Papers 66115

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42827313PubTator, text miningPubMed
42826800PubTator, text miningPubMed
42826304PubTator, text miningPubMed
42822802PubTator, text miningPubMed
42822585PubTator, text miningPubMed
42822048PubTator, text miningPubMed
42821080PubTator, text miningPubMed
42820398PubTator, text miningPubMed
42816404PubTator, text miningPubMed
42813903PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license