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GPX1: glutathione peroxidase 1

1 protein, 3 patents, 0 drugs, 0 trials, 2,821 NIH grants and 6,408 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolGPX1HGNC
Nameglutathione peroxidase 1HGNC
NCBI Gene ID2876NCBI Gene
HGNC IDHGNC:4553HGNC
EnsemblENSG00000233276NCBI Gene
AliasesGPXD, GSHPX1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P07203Glutathione peroxidase 12031Ensembl, GeneID, HGNCUniProt

Patents 3

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1447875P07203Espacenet
WO 2025163153 A22025-08-072P07203Espacenet
WO 2024231419 A12024-11-143P07203Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2821

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA086862Cancer Center Support Grant172,025NIH's project files
P30ES005605Environmental Health Sciences Research Center142,025NIH's project files
R01ES007331Mechanisms of Methylmercury Induced Neuronal Toxicity142,025NIH's project files
P30CA033572Cancer Center Support Grant112,025NIH's project files
R01ES010563Mechanisms of Manganese Neurotoxicity112,025NIH's project files
P30CA016672Cancer Center Support Grant92,025NIH's project files
P30ES010126UNC Center for Environmental Health and Susceptibility92,025NIH's project files
P42ES013661Iowa Superfund Research Program: Airborne PCBs: Sources, Exposures, Toxicities, Remediation82,025NIH's project files
ZIABC010677NADPH Oxidases as Novel Targets for Cancer Therapy82,025NIH's project files
P20GM103466HAWAII INBRE V PROGRAM72,025NIH's project files

Papers 6408

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42797298PubTator, text miningPubMed
42796340PubTator, text miningPubMed
42785059PubTator, text miningPubMed
42780667PubTator, text miningPubMed
42774487PubTator, text miningPubMed
42770141PubTator, text miningPubMed
42752304PubTator, text miningPubMed
42731384PubTator, text miningPubMed
42713210PubTator, text miningPubMed
42705160PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license