Gene · 2878
GPX3: glutathione peroxidase 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. GPX3: glutathione peroxidase 3. Genes, record 2878. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2878
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P22352 | Glutathione peroxidase 3 | 226 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents7
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 10639 | P22352 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6535 | P22352 | Espacenet |
| WO 2025163153 A2 | 2025-08-07 | 39 | P22352 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6535 | P22352 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 10639 | P22352 | Espacenet |
| WO 2024231419 A1 | 2024-11-14 | 5 | P22352 | Espacenet |
| JP 2024038290 A | 2024-03-19 | 41 | P22352 | Espacenet |
Drugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,519
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | GPX3 papers | Newest fiscal year |
|---|---|---|---|
| R01GM102187 | Chemical Tools for Probing Cysteine Sulfenation and Sulfination Redox Biology | 13 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 6 | 2025 |
| P30DK058404 | Molecular and Cellular Basis for Digestive Diseases | 6 | 2025 |
| ZIACP010121 | Molecular Epidemiology Studies of Occupational and Environmental Exposures | 6 | 2025 |
| P30CA033572 | Cancer Center Support Grant | 5 | 2025 |
| P30ES006694 | Southwest Environmental Health Sciences Center | 5 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 4 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 4 | 2025 |
| P30ES005605 | Environmental Health Sciences Research Center | 4 | 2025 |
1 to 10 of 1,519Source NIH's project files
See all 1,519 nih grantsPapers2,921
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Transcriptome-based epigenetic screening identifies DNA hypermethylation signatures as prognostic biomarkers in oral squamous cell carcinoma. | Mol Biomed | 2026 | 42749952 | PubTator, text mining | PubMed |
| Effects of Hyperbaric Oxygen Combined with Lycopene on Oxidative Stress and Inflammation in Collegiate Badminton Players After High-Intensity Training. | Nutrients | 2026 | 42739033 | PubTator, text mining | PubMed |
| The GPX3-VCAM1 Axis Gates Pro-Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy. | Adv Sci (Weinh) | 2026 | 42717509 | PubTator, text mining | PubMed |
| GPX3 suppresses lung adenocarcinoma progression through HSPB1 ubiquitination and Hippo pathway activation. | Cell Rep | 2026 | 42684887 | PubTator, text mining | PubMed |
| Transcriptomic Analysis Reveals Core Genes and Mechanisms Linking Grilled Food Toxicants (4-HNE, BaP, PhIP) to NASH-HCC Progression. | Food Sci Nutr | 2026 | 42682783 | PubTator, text mining | PubMed |
| Sex-Associated Proteomic Signatures Persist Independent of Injury Severity and Shock Physiology in Acute Trauma. | Shock | 2026 | 42625553 | PubTator, text mining | PubMed |
| Molecular Mechanisms Governing Vascular Function in Heart Failure. | Arterioscler Thromb Vasc Biol | 2026 | 42619591 | PubTator, text mining | PubMed |
| Integrative transcriptomics and single-cell analysis identify SIX4 as a candidate epithelial target in ovarian cancer and PCOS-associated ovarian dysregulation. | Transl Oncol | 2026 | 42546664 | PubTator, text mining | PubMed |
| Gamete co-incubation duration modulates blastocyst developmental competence in buffalo through regulation of growth factors, steroidogenesis and oxidative stress pathways. | Mol Biol Rep | 2026 | 42489973 | PubTator, text mining | PubMed |
| Alginate oligosaccharides improve breast muscle quality of heat-stressed broilers by modulating oxidative stability, muscle fiber transformation, and lipid metabolism. | Food Chem | 2026 | 42475991 | PubTator, text mining | PubMed |
1 to 10 of 2,921
See all 2,921 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2878
GET https://conductscience.org/api/genes/v1/2878/grants?page=2