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Gene · 2887

GRB10: growth factor receptor bound protein 10

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GRB10: growth factor receptor bound protein 10. Genes, record 2887. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2887

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Gene

Symbol
GRB10
HGNC
Name
growth factor receptor bound protein 10
HGNC
NCBI Gene ID
2887
NCBI Gene
HGNC ID
HGNC:4564
HGNC
Ensembl
ENSG00000106070
NCBI Gene
Aliases
GRB-IR, Grb-10, IRBP, MEG1, RSS
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q13322Growth factor receptor-bound protein 105942Ensembl, GeneID, HGNC

Source UniProt

Patents41

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4641202 A22025-10-295998Q13322Espacenet
JP 2025032204 A2025-03-1129266Q13322Espacenet
JP 2025032204 A2025-03-1129270Q13322Espacenet
KR 1020250017231 A2025-02-045998Q13322Espacenet
JP 2024178415 A2024-12-248168Q13322Espacenet
EP 4461818 A22024-11-1329266Q13322Espacenet
EP 4461818 A22024-11-1329270Q13322Espacenet
JP 2024123008 A2024-09-106391Q13322Espacenet
JP 2024123008 A2024-09-106392Q13322Espacenet
JP 2023058610 A2023-04-2529266Q13322Espacenet

1 to 10 of 41

See all 41 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,361

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGRB10 papersNewest fiscal year
P30CA016672Cancer Center Support Grant92025
U54CA1323831/2 Partnership for the Advancement of Cancer Research: NMSU & Fred Hutch72025
P30CA008748Cancer Center Support Grant62025
P30DK020572Michigan Diabetes Research Center (MDRC)62025
P30DK036836Diabetes Research Center52025
P30DK063491Diabetes Research Center (DRC)52025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant42025
P30ES010126UNC Center for Environmental Health and Susceptibility42025
P30ES017885Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD)42025
R01DK093757Genetic epidemiology of rare and regulatory variants for metabolic traits42025

1 to 10 of 1,361Source NIH's project files

See all 1,361 nih grants

Papers1,547

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Integrative mRNA and miRNA Profiling Identifies Shared and Subtype-Associated PI3K-AKT-mTOR Pathway Dysregulation and Candidate miRNA-Mediated Regulatory Interactions in Endometriosis-Associated Ovarian Cancers (EAOCs).
Biomedicines202642792733PubTator, text miningPubMed
Shared genetic basis of sarcopenia and osteoporosis: insights from GWAS and multi-omics analyses.J Bone Miner Metab202642763834PubTator, text miningPubMed
CircHMGB2 Acts as a Molecular Decoy for IGF2BP1 to Promote Cisplatin Resistance via Grb10/Akt Signaling in Chondrosarcoma.Acta Orthop Belg202642561431PubTator, text miningPubMed
Druggable Genome-Wide Mendelian Randomization Identifies Therapeutic Targets and DNA Methylation-Mediated Regulation in Urological Malignancies.Technol Cancer Res Treat202642098041PubTator, text miningPubMed
Skeletal Muscle and Circulating microRNAs Adaptations to 12-Week HIIT With or Without L-Citrulline in Obese Older Adults.J Cachexia Sarcopenia Muscle202641933456PubTator, text miningPubMed
Identification of plasma exosome circRNA as potential novel biomarkers for DLBCL and circrna-miRNA-mRNA network analysis.Clin Exp Med202641925757PubTator, text miningPubMed
Diterpene Molecular Glue Stabilizes Protein-Protein Interactions of a Disordered Phosphoprotein that Controls Translational Repression.JACS Au202641755863PubTator, text miningPubMed
Functional characterisation of tumour suppressor PDCD4 reveals previously undisclosed role in the control of cell adhesion.Nucleic Acids Res202641626692PubTator, text miningPubMed
Uncovering the Structural Logic of Grb7: From Domain Mutagenesis to Therapeutic Implications in Cancer Signaling.J Mol Recognit202641365692PubTator, text miningPubMed
RNA-binding protein GIGYF2 promotes colorectal cancer progression through activation of the METTL3/SERP1/STAT3 axis in an m6A-IGF2BP2-dependent manner.Biochem Pharmacol202641130307PubTator, text miningPubMed

1 to 10 of 1,547

See all 1,547 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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