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Gene · 28884

IGKV2D-26: immunoglobulin kappa variable 2D-26

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. IGKV2D-26: immunoglobulin kappa variable 2D-26. Genes, record 28884. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/28884

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Gene

Symbol
IGKV2D-26
HGNC
Name
immunoglobulin kappa variable 2D-26
HGNC
NCBI Gene ID
28884
NCBI Gene
HGNC ID
HGNC:5798
HGNC
Ensembl
ENSG00000211623
NCBI Gene
Aliases
A5, IGKV2D26
NCBI Gene
Type
pseudo
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
A0A0A0MRZ7Immunoglobulin kappa variable 2D-261200Ensembl, HGNC

Source UniProt

Patents5

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1910726A0A0A0MRZ7Espacenet
JP 2025517970 A2025-06-1210726A0A0A0MRZ7Espacenet
US 11446398 B22022-09-2039845A0A0A0MRZ7Espacenet
JP 2022524081 A2022-04-27142816A0A0A0MRZ7Espacenet
WO 2020043864 A12020-03-051310A0A0A0MRZ7Espacenet

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,572

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleIGKV2D-26 papersNewest fiscal year
R01DK018381Studies on the structure of basement membranes192025
P30DK058404Molecular and Cellular Basis for Digestive Diseases72025
P30CA016672Cancer Center Support Grant62025
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant62025
P30CA068485Cancer Center Support Grant62025
R01CA212608Probing RAS-mediated Signaling with Monobody Inhibitors62025
R01HL131836Structural Transition of Cellular Integrins and Applications Thereof62025
P30CA008748Cancer Center Support Grant52025
P30CA014051Cancer Center Support (Core) Grant52025
P30CA030199Cancer Center Support Grant (CCSG)52025

1 to 10 of 2,572Source NIH's project files

See all 2,572 nih grants

Papers3,317

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
GABAA receptor α subunit distribution is congruent with functional anatomical areas in the human cortex.J Cereb Blood Flow Metab202642802645PubTator, text miningPubMed
Lymph node extracellular matrix skews the immune function of human fibroblastic reticular cells.iScience202642780986PubTator, text miningPubMed
Targeting α5-GABAA receptors to restore dopamine system function in a translationally relevant model of perimenopausal psychosis.Psychopharmacology (Berl)202642776198PubTator, text miningPubMed
Structural basis for activation and potentiation in a human α5β3 GABAA receptor.Nat Commun202642297817PubTator, text miningPubMed
Alterations in the Components of the GABA-Glutamate System During ZIKV Infection: A Neuroscience Approach.Int J Mol Sci202642278369PubTator, text miningPubMed
Targeting the H/KRAS α4-β6-α5 Allosteric Lobe with Macrocyclic Peptides.ACS Med Chem Lett202642157834PubTator, text miningPubMed
Structural and mechanistic insights into α2β1 and α5β1 integrin targeting by bioengineered extracellular vesicles originating from lung cancer cells.Sci Rep202641896296PubTator, text miningPubMed
Ligand-specific conformational dynamics of the α2A-adrenergic receptor revealed by hydrogen-deuterium exchange mass spectrometry.Structure202641812653PubTator, text miningPubMed
Polystyrene Nanoparticles Disrupt Oxidative Phosphorylation and Impair Placental Development in Mice.Toxics202641745832PubTator, text miningPubMed
The β-amyloid-induced increased tonic conductance, impaired long-term potentiation and cognitive deficits characteristic of Alzheimer's disease are reversed by an α5 inverse agonist of the GABA type A receptor.
Neuropharmacology202641740903PubTator, text miningPubMed

1 to 10 of 3,317

See all 3,317 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/28884

GET https://conductscience.org/api/genes/v1/28884/grants?page=2