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Gene · 28885

IGKV2D-24: immunoglobulin kappa variable 2D-24 (non-functional)

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. IGKV2D-24: immunoglobulin kappa variable 2D-24 (non-functional). Genes, record 28885. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/28885

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Gene

Symbol
IGKV2D-24
HGNC
Name
immunoglobulin kappa variable 2D-24 (non-functional)
HGNC
NCBI Gene ID
28885
NCBI Gene
HGNC ID
HGNC:5797
HGNC
Ensembl
ENSG00000241566
NCBI Gene
Aliases
A7, IGKV2D24
NCBI Gene
Type
other
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
A0A075B6R9Probable non-functional immunoglobulin kappa variable 2D-241200Ensembl, HGNC

Source UniProt

Patents4

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1914057A0A075B6R9Espacenet
JP 2025517970 A2025-06-1214057A0A075B6R9Espacenet
US 11446398 B22022-09-2039844A0A075B6R9Espacenet
JP 2022524081 A2022-04-27142815A0A075B6R9Espacenet

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,367

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleIGKV2D-24 papersNewest fiscal year
ZIAES090089Modulation Of Neuronal Channels and Receptors in the Brain122025
R01MH077681Cholinergic Contribution to Circuits Guiding Behavioral Responses to Stressors72025
P30CA013330Cancer Center Support Grant62025
P51OD011092Support for National Primate Research Center52025
T32MH015442Development of Psychopathology, Psychobiology, & Behavior52025
P30CA044579University of Virginia Cancer Center Support Grant42025
P30EY003039UAB Core Grant for Vision Research42025
ZIACP010206Human Papillomavirus (HPV) Natural History, Genomics and Risk Assessment42025
K12DA000167Clinician Scientist Training Program (CSTP)32025
P20GM103466HAWAII INBRE V PROGRAM32025

1 to 10 of 1,367Source NIH's project files

See all 1,367 nih grants

Papers2,118

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
The CAGE Framework (Calcium-Gated Excitability): From Single Neurotransmitters to Calcium States in the Tumor Microenvironment.Int J Mol Sci202642737834PubTator, text miningPubMed
Peptides containing SARS-CoV-2 spike-protein residues are antagonists of α7 and α9α10 nAChRs and modulate interleukin-1β release from human monocytic THP-1 cells.J Biol Chem202642556725PubTator, text miningPubMed
Nicotinic acetylcholine receptors in pain modulation.Front Pharmacol202642256394PubTator, text miningPubMed
Structural basis for RISC assembly of human Argonaute2.Mol Cell202642190652PubTator, text miningPubMed
Rabies virus glycoprotein variants modulate neuronal nicotinic receptors in a conformation-dependent manner.Sci Rep202642162234PubTator, text miningPubMed
Hybrid channels containing the dupα7 subunit mediate resistance to α7-nAChR targeting therapy in metastatic melanoma.Am J Physiol Cell Physiol202641989766PubTator, text miningPubMed
Nicotine Suppresses Human Memory Th Cell Subsets With Preferential Effects on Central Memory Th Cells in an α7 Nicotinic Acetylcholine Receptor-Dependent Manner.Eur J Immunol202641928597PubTator, text miningPubMed
The amino terminal domain of the human α7 nicotinic acetylcholine receptor subunit leads to the functional expression of human/insect receptors.Br J Pharmacol202641909918PubTator, text miningPubMed
Putative α7-selective ligands interact with α9-containing nicotinic acetylcholine receptors and modulate immune functions of human mononuclear phagocytes.Front Immunol202641890755PubTator, text miningPubMed
Combined Nudged Elastic Band and Markov State Models Uncover Distinct BAX Activation Pathways by Bim Peptide and a Small Molecule.JACS Au202641755821PubTator, text miningPubMed

1 to 10 of 2,118

See all 2,118 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/28885

GET https://conductscience.org/api/genes/v1/28885/grants?page=2