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Gene · 28906

IGKV6-21: immunoglobulin kappa variable 6-21 (non-functional)

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. IGKV6-21: immunoglobulin kappa variable 6-21 (non-functional). Genes, record 28906. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/28906

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Gene

Symbol
IGKV6-21
HGNC
Name
immunoglobulin kappa variable 6-21 (non-functional)
HGNC
NCBI Gene ID
28906
NCBI Gene
HGNC ID
HGNC:5836
HGNC
Ensembl
ENSG00000211611
NCBI Gene
Aliases
A26, IGKV621
NCBI Gene
Type
other
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
A0A0C4DH24Immunoglobulin kappa variable 6-211140Ensembl, HGNC

Source UniProt

Patents6

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1910724A0A0C4DH24Espacenet
JP 2025517970 A2025-06-1210724A0A0C4DH24Espacenet
US 11446398 B22022-09-2039872A0A0C4DH24Espacenet
US 11446398 B22022-09-2039873A0A0C4DH24Espacenet
JP 2022524081 A2022-04-27142843A0A0C4DH24Espacenet
JP 2022524081 A2022-04-27142844A0A0C4DH24Espacenet

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants656

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleIGKV6-21 papersNewest fiscal year
P30CA013148Comprehensive Cancer Center Support Grant82025
P30AI027767UAB Center for AIDS Research (CFAR)62025
P30CA138313Medical University of South Carolina - Cancer Center Support Grant42025
P30DK123704MUSC Digestive Disease Research Core Center42025
R01GM130091Quantitative Characterization of Glycopeptide Isomers42025
T32GM132055Cellular, Biochemical and Molecular Sciences Training Program42025
ZIAAI000986Influenza Viral Pathogenesis42025
P01HL151333Molecular and Clinical Glycobiology of the Bone Marrow Environment32025
R01CA160254Serum Glyco-Markers of Early Hepatocellular Carcinoma Using a Mass Spec Approach32025
R01GM115234Regulatory Mechanisms of Glycoprotein Sialylation32025

1 to 10 of 656Source NIH's project files

See all 656 nih grants

Papers1,381

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
ST6GAL1 promotes cancer stem-like cell-associated paclitaxel resistance through the EGFR-mTOR-SOX2/BMI1 axis in non-small cell lung cancer.Cancer Drug Resist202642764906PubTator, text miningPubMed
ST6GAL1-mediated sialyl linkage switching drives cancer-promoting α2,6-sialo-protrusions radiating from anti-inflammatory TAMs.Proc Natl Acad Sci U S A202642640786PubTator, text miningPubMed
Programmable One-Tube Sialic Acid Derivatization Enables Dual-Mode N-Glycomics of Low-Input Samples.Anal Chem202642578856PubTator, text miningPubMed
Sialic Acid Linkage-Specific Alkylamidation-Based Method for N- and O-Glycoproteomic Profiling of Human Plasma.Anal Chem202642421262PubTator, text miningPubMed
Bioorthogonal labeling of sialic acid isomers for detection of glycoconjugates by mass spectrometry imaging and microscopy.Methods Enzymol202642349971PubTator, text miningPubMed
Galacto-Oligosaccharides Reshape Mucin O-Glycan Profiles to Enhance Small Intestinal Barrier Development in Early Life.J Agric Food Chem202642284521PubTator, text miningPubMed
Rab11Bis required for binding and entry of recent H3N2, but not H1N1, influenza A isolates.J Virol202642227759PubTator, text miningPubMed
Siglec-G on B cells restrains the germinal center response by controlling T cell help during positive selection.bioRxiv202642182281PubTator, text miningPubMed
Blood transcriptomic signatures distinguish Mycobacterium avium complex pulmonary disease from colonization: a multicenter cohort study.Emerg Microbes Infect202642175713PubTator, text miningPubMed
Severe hypoxia drives loss of ST6GAL1-mediated α2,6-sialylation in the epicardial secretome impairing angiogenic activity.Biol Open202642052876PubTator, text miningPubMed

1 to 10 of 1,381

See all 1,381 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/28906

GET https://conductscience.org/api/genes/v1/28906/grants?page=2