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IGKV4-1: immunoglobulin kappa variable 4-1

1 protein, 25 patents, 0 drugs, 0 trials, 5,503 NIH grants and 7,822 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolIGKV4-1HGNC
Nameimmunoglobulin kappa variable 4-1HGNC
NCBI Gene ID28908NCBI Gene
HGNC IDHGNC:5834HGNC
EnsemblENSG00000211598NCBI Gene
AliasesB3, IGKV41NCBI Gene
TypeotherNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P06312Immunoglobulin kappa variable 4-112110Ensembl, HGNCUniProt

Patents 25

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1910720P06312Espacenet
EP 4641201 A22025-10-2911151P06312Espacenet
EP 4641203 A22025-10-29326P06312Espacenet
JP 2025138725 A2025-09-252627P06312Espacenet
JP 2025517967 A2025-06-12326P06312Espacenet
JP 2025517969 A2025-06-1211151P06312Espacenet
JP 2025517970 A2025-06-1210720P06312Espacenet
KR 1020250017230 A2025-02-04326P06312Espacenet
JP 2023145599 A2023-10-112627P06312Espacenet
JP 2023529206 A2023-07-0781P06312Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 5503

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R01HL019278Platelet Integrin AlphaIIbBeta3 Structure, Activation, and Ligand Binding: Fibrinogen, Fibrin, D-dimer, and von Willebrand Factor282,025NIH's project files
P30CA030199Cancer Center Support Grant (CCSG)142,025NIH's project files
P30CA093373Cancer Center Support Grant P30132,025NIH's project files
R01HL131836Structural Transition of Cellular Integrins and Applications Thereof132,025NIH's project files
P30CA008748Cancer Center Support Grant122,025NIH's project files
P30CA016672Cancer Center Support Grant122,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program92,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award82,025NIH's project files
P20GM103408Idaho INBRE Program62,025NIH's project files
P30CA056036Translational Research in Cancer62,025NIH's project files

Papers 7822

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42746985PubTator, text miningPubMed
42638473PubTator, text miningPubMed
42636365PubTator, text miningPubMed
42400907PubTator, text miningPubMed
42363618PubTator, text miningPubMed
42322748PubTator, text miningPubMed
42297817PubTator, text miningPubMed
42158284PubTator, text miningPubMed
42123623PubTator, text miningPubMed
42080063PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license