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Gene · 28923

IGKV2-24: immunoglobulin kappa variable 2-24

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. IGKV2-24: immunoglobulin kappa variable 2-24. Genes, record 28923. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/28923

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Gene

Symbol
IGKV2-24
HGNC
Name
immunoglobulin kappa variable 2-24
HGNC
NCBI Gene ID
28923
NCBI Gene
HGNC ID
HGNC:5781
HGNC
Ensembl
ENSG00000241294
NCBI Gene
Aliases
A23, IGKV224
NCBI Gene
Type
other
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
A0A0C4DH68Immunoglobulin kappa variable 2-241200Ensembl, HGNC

Source UniProt

Patents6

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1914310A0A0C4DH68Espacenet
JP 2025517970 A2025-06-1214310A0A0C4DH68Espacenet
US 11446398 B22022-09-2039834A0A0C4DH68Espacenet
US 11446398 B22022-09-2039835A0A0C4DH68Espacenet
JP 2022524081 A2022-04-27142805A0A0C4DH68Espacenet
JP 2022524081 A2022-04-27142806A0A0C4DH68Espacenet

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants779

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleIGKV2-24 papersNewest fiscal year
ZIAAI000986Influenza Viral Pathogenesis52025
P30CA008748Cancer Center Support Grant32025
P30CA138313Medical University of South Carolina - Cancer Center Support Grant32025
P30DK123704MUSC Digestive Disease Research Core Center32025
R01AI165692Automated chemo-enzymatic synthesis of N-glycans for host-pathogen interactions32025
R01CA160254Serum Glyco-Markers of Early Hepatocellular Carcinoma Using a Mass Spec Approach32025
R01GM082946AAV capsids and their cellular interactions32025
T32GM132055Cellular, Biochemical and Molecular Sciences Training Program32025
ZIAAI000307Poxvirus Biology32025
ZIAAI005022Antibody Neutralization Mechanisms32025

1 to 10 of 779Source NIH's project files

See all 779 nih grants

Papers1,286

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
α2,3-sialylation on human naïve T cells restrains bispecific engager-mediated anti-tumor immunity.bioRxiv202642620328PubTator, text miningPubMed
Programmable One-Tube Sialic Acid Derivatization Enables Dual-Mode N-Glycomics of Low-Input Samples.Anal Chem202642578856PubTator, text miningPubMed
Sialic Acid Linkage-Specific Alkylamidation-Based Method for N- and O-Glycoproteomic Profiling of Human Plasma.Anal Chem202642421262PubTator, text miningPubMed
Bioorthogonal labeling of sialic acid isomers for detection of glycoconjugates by mass spectrometry imaging and microscopy.Methods Enzymol202642349971PubTator, text miningPubMed
Galacto-Oligosaccharides Reshape Mucin O-Glycan Profiles to Enhance Small Intestinal Barrier Development in Early Life.J Agric Food Chem202642284521PubTator, text miningPubMed
α2,3-Sialyltransferase (ST3Gal1) regulates endometrioid-type epithelial ovarian cancer cell migration and invasion via VEGF-R2/JAK2/STAT3 signaling cascades.Int J Gynaecol Obstet202642080626PubTator, text miningPubMed
De novo biosynthesis of 3'-sialyllactosamine in Escherichia coli via integrated metabolic and protein engineering.Bioresour Technol202642013939PubTator, text miningPubMed
Increased levels of α2-3- and α2-6-linked sialic acids during airway inflammation govern influenza A binding to peripheral airway mucins in a subtype-dependent manner.Front Immunol202641909675PubTator, text miningPubMed
Cancer cell-derived sialylated IgG interacting with Siglec-7/9/10 is a potential immunotherapeutic target in pancreatic cancer.Cell Rep Med202641850238PubTator, text miningPubMed
Glycoengineering CAR-T cells to overcome galectin-3-mediated immunosuppression.Front Immunol202641789075PubTator, text miningPubMed

1 to 10 of 1,286

See all 1,286 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/28923

GET https://conductscience.org/api/genes/v1/28923/grants?page=2