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GRN: granulin precursor

1 protein, 167 patents, 0 drugs, 0 trials, 3,703 NIH grants and 6,987 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolGRNHGNC
Namegranulin precursorHGNC
NCBI Gene ID2896NCBI Gene
HGNC IDHGNC:4601HGNC
EnsemblENSG00000030582NCBI Gene
AliasesCLN11, FTD2, GEP, GP88, PCDGF, PEPI, PGRNNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P28799Progranulin5938Ensembl, GeneID, HGNCUniProt

Patents 167

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026210020 A12026-10-0875P28799Espacenet
WO 2026174322 A12026-08-201P28799Espacenet
JP 2026062601 A52026-04-247P28799Espacenet
JP 2026067851 A2026-04-21277P28799Espacenet
JP 2026510614 A2026-04-094P28799Espacenet
EP 4720313 A12026-04-0810P28799Espacenet
JP 2026509301 A2026-03-1714P28799Espacenet
US 12570963 B22026-03-1067P28799Espacenet
JP 2026004568 A2026-01-1448200P28799Espacenet
JP 2026501108 A2026-01-1416P28799Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3703

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P01AG019724Frontotemporal Dementia: Genes, Images, and Emotions1802,025NIH's project files
U24AG021886National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)912,025NIH's project files
P30AG062422New Approaches to Dementia Heterogeneity502,025NIH's project files
U19AG063911ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration, Cycle 2 (ALLFTD2)472,025NIH's project files
T32AG023481Multidisciplinary Research Fellowship in Alzheimer’s disease and Related Dementias292,025NIH's project files
P01AG026276Antecedent Biomarkers for Alzheimer Disease: The Adult Children Study262,025NIH's project files
P30AG062421Massachusetts Alzheimer's Disease Research Center (MADRC)262,025NIH's project files
P30AG062677Mayo Alzheimer's Disease Research Center242,025NIH's project files
P30AG066509University of Washington Alzheimer's Disease Research Center242,025NIH's project files
R01NS050915Primary Progressive Aphasia: Cognition, Anatomy and Progression232,025NIH's project files

Papers 6987

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42823745PubTator, text miningPubMed
42823455PubTator, text miningPubMed
42818922PubTator, text miningPubMed
42814712PubTator, text miningPubMed
42808521PubTator, text miningPubMed
42791463PubTator, text miningPubMed
42789703PubTator, text miningPubMed
42782355PubTator, text miningPubMed
42779687PubTator, text miningPubMed
42778943PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license