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ANPEP: alanyl aminopeptidase, membrane

1 protein, 70 patents, 1 drug, 9 trials, 4,249 NIH grants and 12,750 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolANPEPHGNC
Namealanyl aminopeptidase, membraneHGNC
NCBI Gene ID290NCBI Gene
HGNC IDHGNC:500HGNC
EnsemblENSG00000166825NCBI Gene
AliasesAP-M, AP-N, APN, CD13, GP150, LAP1, P150, PEPN, gp150, hAPN, p150NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P15144Aminopeptidase N96715Ensembl, GeneID, HGNCUniProt

Patents 70

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026508054 A2026-03-1032P15144Espacenet
EP 4650780 A22025-11-193979P15144Espacenet
WO 2025228986 A12025-11-0635P15144Espacenet
EP 4644537 A12025-11-0535P15144Espacenet
EP 4640849 A22025-10-29515P15144Espacenet
EP 4641201 A22025-10-293558P15144Espacenet
JP 2025529142 A2025-09-04403P15144Espacenet
EP 4608873 A12025-09-0332P15144Espacenet
US 12371689 B22025-07-29403P15144Espacenet
JP 2025519096 A2025-06-24515P15144Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
TOSEDOSTATCHEMBL2103847Aminopeptidase inhibitorINHIBITORChEMBL

Trials 9

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT02452346TOSEDOSTATPHASE22018-06-12ClinicalTrials.gov
NCT02352831TOSEDOSTATPHASE1/PHASE22018-12-17ClinicalTrials.gov
NCT01636609TOSEDOSTATPHASE1ClinicalTrials.gov
NCT01567059TOSEDOSTATPHASE2ClinicalTrials.gov
NCT01180426TOSEDOSTATPHASE2ClinicalTrials.gov
NCT00780598TOSEDOSTATPHASE2ClinicalTrials.gov
NCT00737555TOSEDOSTATPHASE1ClinicalTrials.gov
NCT00689000TOSEDOSTATPHASE1/PHASE2ClinicalTrials.gov
NCT00522938TOSEDOSTATPHASE1/PHASE2ClinicalTrials.gov

NIH grants 4249

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant742,025NIH's project files
P30CA008748Cancer Center Support Grant412,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)412,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant142,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant132,025NIH's project files
P30CA006973Regional Oncology Research Center122,025NIH's project files
P30CA047904Cancer Center Support Grant112,025NIH's project files
U10CA180886COG NCTN Network Group Operations Center - Year 11 STAR Act MCI and PEC Supplement112,025NIH's project files
P30CA015704Cancer Center Support Grant102,025NIH's project files
U10CA180899Children's Oncology Group Statistics and Data Center92,025NIH's project files

Papers 12750

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42820296PubTator, text miningPubMed
42804095PubTator, text miningPubMed
42794595PubTator, text miningPubMed
42788447PubTator, text miningPubMed
42760285PubTator, text miningPubMed
42749892PubTator, text miningPubMed
42749891PubTator, text miningPubMed
42719294PubTator, text miningPubMed
42688362PubTator, text miningPubMed
42667975PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license