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Gene · 291

SLC25A4: solute carrier family 25 member 4

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SLC25A4: solute carrier family 25 member 4. Genes, record 291. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/291

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Gene

Symbol
SLC25A4
HGNC
Name
solute carrier family 25 member 4
HGNC
NCBI Gene ID
291
NCBI Gene
HGNC ID
HGNC:10990
HGNC
Ensembl
ENSG00000151729
NCBI Gene
Aliases
AAC1, ANT, ANT 1, ANT1, MTDPS12, MTDPS12A, PEO2, PEO3, PEOA2, T1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P12235ADP/ATP translocase 12980Ensembl, GeneID, HGNC

Source UniProt

Patents30

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1464257P12235Espacenet
EP 4650780 A22025-11-193127P12235Espacenet
JP 2025529142 A2025-09-044097P12235Espacenet
US 12371689 B22025-07-294097P12235Espacenet
JP 2025517970 A2025-06-123127P12235Espacenet
US 11708396 B22023-07-251397P12235Espacenet
US 11446398 B22022-09-2080926P12235Espacenet
US 11400116 B22022-08-021937P12235Espacenet
JP 2022524081 A2022-04-27183897P12235Espacenet
US 11078247 B22021-08-0310436P12235Espacenet

1 to 10 of 30

See all 30 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,073

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSLC25A4 papersNewest fiscal year
ZIAES065078Molecular Characterization Of The Mitochondrial Dna Polymerase62025
ZIAES065080Human Mitochondrial Dna Polymerase With Anti-hiv Nucleotides52025
P30CA016672Cancer Center Support Grant32025
P30CA076292Moffitt Cancer Center Support Grant32025
R01AG011085Ubiquitin‐mediated proteolysis and cell cycle control32025
R01NS083726Personalized Functional Genomics for Mitochondrial Encephalopathy Gene Discovery32025
P30CA008748Cancer Center Support Grant22025
P30CA072720Cancer Center Support Grant22025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant22025
P30CA138313Medical University of South Carolina - Cancer Center Support Grant22025

1 to 10 of 1,073Source NIH's project files

See all 1,073 nih grants

Papers1,498

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Dual Graphene Oxide-Based Multigene Delivery for Cancer Elimination via Stromal and Immune Reprogramming.Int J Biomater202642707720PubTator, text miningPubMed
A Novel SLC25A4 Variant Causing Mitochondrial Dysfunction, Myopathy and Cardiomyopathy: A Functional and Molecular Characterization.Int J Mol Sci202642589632PubTator, text miningPubMed
Machine learning, WGCNA and molecular docking identify SLC transporter genes as biomarkers and drug targets in Helicobacter pylori-associated carcinogenesis.Bioorg Chem202642520516PubTator, text miningPubMed
Integrating bulk RNA-seq, Mendelian randomization and single-cell RNA-seq to elucidate the roles of lactate metabolism related markers-SLC25A4 and keratinocyte in the pathogenesis of psoriasis.Front Immunol202642292364PubTator, text miningPubMed
Elucidating the Neural Basis of Bipolar Disorder - Secondary Publication.JMA J202642266798PubTator, text miningPubMed
Transglutaminase and its role in Alzheimer's disease: focus on mitochondria, aging, defective mitophagy, synaptic degeneration, and metabolomics.Geroscience202642185591PubTator, text miningPubMed
Progression of human osteosarcoma with altered ANT1/SLC25a4 expression.Kans J Med202642137380PubTator, text miningPubMed
Identification of Mitochondrial Signature Biomarkers and Molecular Mechanisms in Atherosclerotic Tissues and Blood: Combined Single-Cell and Bulk RNA Sequencing Analysis.Mol Neurobiol202642032157PubTator, text miningPubMed
Hybrid extracellular vesicles drive irreversible mitochondria damage and TCA metabolite deficiency-related chondrocyte senescence.Innovation (Camb)202641970715PubTator, text miningPubMed
Proteomic analysis reveals distinct gene regulatory functions of the paralogs MAGOH and MAGOHB in cell proliferation.Biochim Biophys Acta Gene Regul Mech202641956154PubTator, text miningPubMed

1 to 10 of 1,498

See all 1,498 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/291

GET https://conductscience.org/api/genes/v1/291/patents?page=2