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PYCARD: PYD and CARD domain containing

1 protein, 90 patents, 0 drugs, 0 trials, 4,300 NIH grants and 10,144 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPYCARDHGNC
NamePYD and CARD domain containingHGNC
NCBI Gene ID29108NCBI Gene
HGNC IDHGNC:16608HGNC
EnsemblENSG00000103490NCBI Gene
AliasesASC, CARD5, TMS, TMS-1, TMS1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q9ULZ3Apoptosis-associated speck-like protein containing a CARD19518Ensembl, GeneID, HGNCUniProt

Patents 90

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026190322 A12026-09-171Q9ULZ3Espacenet
EP 4650780 A22025-11-191225Q9ULZ3Espacenet
EP 4641202 A22025-10-294434Q9ULZ3Espacenet
KR 1020250134595 A2025-09-111Q9ULZ3Espacenet
JP 2025529128 A2025-09-041Q9ULZ3Espacenet
EP 4581044 A12025-07-091Q9ULZ3Espacenet
JP 2025517970 A2025-06-121225Q9ULZ3Espacenet
KR 1020250017231 A2025-02-044434Q9ULZ3Espacenet
US 12178845 B22024-12-313Q9ULZ3Espacenet
US 12162916 B22024-12-101Q9ULZ3Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4300

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R37AI101935Inflammatory Caspases in Innate Immunity and Inflammation472,025NIH's project files
R01AI124346Innate immune signaling and stress response442,025NIH's project files
R35CA253095Innate immune sensors, inflammasomes, and inflammasome-mediated processes in cancer272,025NIH's project files
R01AI124491NLRP1 and CARD8 Inflammasomes: Assembly, Regulation and Stress Sensing252,025NIH's project files
P30CA008748Cancer Center Support Grant242,025NIH's project files
R01AI160179Targeting innate immune pathways, and inflammatory cell death in cytokine-mediated diseases192,025NIH's project files
R37AI063331Cryopyrin/NLRP3 Signaling in Inflammation and Innate Immunity152,025NIH's project files
P30CA016672Cancer Center Support Grant142,025NIH's project files
R01AI137168Characterizing the Mechanism of DPP8/9 Inhibitor-Induced Pyroptosis142,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award132,025NIH's project files

Papers 10144

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42819011PubTator, text miningPubMed
42807349PubTator, text miningPubMed
42801360PubTator, text miningPubMed
42790665PubTator, text miningPubMed
42783502PubTator, text miningPubMed
42774483PubTator, text miningPubMed
42769579PubTator, text miningPubMed
42738891PubTator, text miningPubMed
42732454PubTator, text miningPubMed
42714851PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license