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Gene · 2911

GRM1: glutamate metabotropic receptor 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GRM1: glutamate metabotropic receptor 1. Genes, record 2911. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2911

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Gene

Symbol
GRM1
HGNC
Name
glutamate metabotropic receptor 1
HGNC
NCBI Gene ID
2911
NCBI Gene
HGNC ID
HGNC:4593
HGNC
Ensembl
ENSG00000152822
NCBI Gene
Aliases
GPRC1A, MGLU1, MGLUR1, PPP1R85, SCA44, SCAR13, mGlu1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q13255Metabotropic glutamate receptor 11,1948Ensembl, GeneID, HGNC

Source UniProt

Patents38

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1447787Q13255Espacenet
JP 2026004568 A2026-01-1447788Q13255Espacenet
EP 4650780 A22025-11-193178Q13255Espacenet
EP 4641201 A22025-10-292743Q13255Espacenet
JP 2025529142 A2025-09-041882Q13255Espacenet
US 12371689 B22025-07-291882Q13255Espacenet
JP 2025517969 A2025-06-122743Q13255Espacenet
JP 2025517970 A2025-06-123178Q13255Espacenet
JP 2025032204 A2025-03-1129384Q13255Espacenet
JP 2025032204 A2025-03-1129386Q13255Espacenet

1 to 10 of 38

See all 38 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,035

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGRM1 papersNewest fiscal year
R01MH062646Regulation of Signaling by mGluR5392025
R01NS031373Functions of Metabotropic Glutamate Receptor Subtypes372025
P30CA072720Cancer Center Support Grant122025
ZIAMH002793PET Radiopharmaceutical Sciences72025
P30CA022453CANCER CENTER SUPPORT GRANT62025
P50HD103537Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at Vanderbilt62025
R01MH084894Function of GPCR heteromeric complexes in brain62025
R25ES020721Summer Research Experience Programs (R25)62025
ZIAMH002857Glutamatergic Modulators for Rapid and Sustained Antidepressant Effect62025
P30CA008748Cancer Center Support Grant52025

1 to 10 of 2,035Source NIH's project files

See all 2,035 nih grants

Papers2,971

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Pharmacological targeting of bunyavirus-induced synaptic impairment prevents neuronal hyperexcitability.Nat Commun202642823442PubTator, text miningPubMed
Clinical Characteristics of Japanese Cases of Anti-Metabotropic Glutamate Receptor Type 1 Antibody-Associated Cerebellar Ataxia.Cerebellum202642814184PubTator, text miningPubMed
Emerging genetics of sleep and circadian disorders.Curr Opin Pediatr202642750652PubTator, text miningPubMed
Group I metabotropic glutamate receptors are required for the induction of long-term depression at the medial perforant path-dentate gyrus synapse.J Neurophysiol202642716522PubTator, text miningPubMed
Inflammatory bowel disease and prostate cancer: from epidemiological controversy to mechanistic hypotheses.Front Immunol202642694773PubTator, text miningPubMed
A case of subperiosteal clavicular chondromyxoid fibroma in a 52-year-old man: emphasis on diagnostic utility of GRM1 immunohistochemistry.Skeletal Radiol202642680879PubTator, text miningPubMed
Chondromyxoid fibroma with limited or no chondromyxoid stroma: A clinicopathological study of 3 cases.Virchows Arch202642525261PubTator, text miningPubMed
Biochemical Pathways of Neuroplasticity in Sport Skill Acquisition: From Neuroscience to Coaching Practice.Brain Sci202642512469PubTator, text miningPubMed
DNA Methylation at Core N-Methyl-D-Aspartate (NMDA) Receptor Genes Reveals a Glutamatergic Signature of Aging in Post-COVID Whole Blood With Implications for Long-COVID Neuropsychiatric Sequelae.Cureus202642471918PubTator, text miningPubMed
G protein selectivity in group I metabotropic glutamate receptors.Sci Adv202642430471PubTator, text miningPubMed

1 to 10 of 2,971

See all 2,971 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2911

GET https://conductscience.org/api/genes/v1/2911/patents?page=2