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TBK1: TANK binding kinase 1

1 protein, 45 patents, 0 drugs, 0 trials, 6,157 NIH grants and 11,455 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTBK1HGNC
NameTANK binding kinase 1HGNC
NCBI Gene ID29110NCBI Gene
HGNC IDHGNC:11584HGNC
EnsemblENSG00000183735NCBI Gene
AliasesAIARV, FTDALS4, IIAE8, NAK, T2KNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q9UHD2Serine/threonine-protein kinase TBK172925Ensembl, GeneID, HGNCUniProt

Patents 45

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-195833Q9UHD2Espacenet
JP 2025517970 A2025-06-125833Q9UHD2Espacenet
EP 4541373 A12025-04-233Q9UHD2Espacenet
JP 2025062601 A2025-04-1493Q9UHD2Espacenet
US 11878018 B12024-01-239Q9UHD2Espacenet
WO 2023243689 A2023-12-213Q9UHD2Espacenet
US 11725035 B22023-08-153Q9UHD2Espacenet
US 11446398 B22022-09-2086654Q9UHD2Espacenet
JP 2022524081 A2022-04-27189625Q9UHD2Espacenet
JP 2022523514 A2022-04-2593Q9UHD2Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 6157

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant402,025NIH's project files
P30CA016672Cancer Center Support Grant402,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant242,025NIH's project files
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success202,025NIH's project files
P01AG019724Frontotemporal Dementia: Genes, Images, and Emotions182,025NIH's project files
P01CA019014Viral Oncogenesis, Latency, and Replication182,025NIH's project files
P01AI063302The intersection of innate and adaptive immunity to intracellular pathogens172,025NIH's project files
P30CA016086Cancer Center Support Grant162,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award152,025NIH's project files
P30CA142543UT Southwestern Medical Center Simmons Comprehensive Cancer Center142,025NIH's project files

Papers 11455

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42827098PubTator, text miningPubMed
42825361PubTator, text miningPubMed
42816627PubTator, text miningPubMed
42809925PubTator, text miningPubMed
42785749PubTator, text miningPubMed
42785451PubTator, text miningPubMed
42784634PubTator, text miningPubMed
42782733PubTator, text miningPubMed
42780028PubTator, text miningPubMed
42773483PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license