Gene · 2917
GRM7: glutamate metabotropic receptor 7
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. GRM7: glutamate metabotropic receptor 7. Genes, record 2917. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2917
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q14831 | Metabotropic glutamate receptor 7 | 915 | 6 | Ensembl, GeneID, HGNC |
Source UniProt
Patents43
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 47811 | Q14831 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 7470 | Q14831 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 1113 | Q14831 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 7443 | Q14831 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1888 | Q14831 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1888 | Q14831 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 1113 | Q14831 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 7443 | Q14831 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 7470 | Q14831 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 29404 | Q14831 | Espacenet |
1 to 10 of 43
See all 43 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,231
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | GRM7 papers | Newest fiscal year |
|---|---|---|---|
| R01NS031373 | Functions of Metabotropic Glutamate Receptor Subtypes | 34 | 2025 |
| R01MH062646 | Regulation of Signaling by mGluR5 | 20 | 2025 |
| ZIAMH002857 | Glutamatergic Modulators for Rapid and Sustained Antidepressant Effect | 8 | 2025 |
| ZIAMH002927 | Neurobiology and Target Validation of Novel Therapeutic Agents in Mood Disorders | 6 | 2025 |
| ZIAHD001205 | Cellular And Synaptic Physiology Of Hippocampal Interneurons | 5 | 2025 |
| R01MH084894 | Function of GPCR heteromeric complexes in brain | 4 | 2025 |
| T32MH065215 | Postdoctoral Program in Functional Neurogenomics | 4 | 2025 |
| ZIANS002994 | Subunit-Specific Regulation Of Glutamate Receptors | 4 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 3 | 2025 |
| P30ES010126 | UNC Center for Environmental Health and Susceptibility | 3 | 2025 |
1 to 10 of 1,231Source NIH's project files
See all 1,231 nih grantsPapers1,307
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Integrated network toxicology and multiomics analyses reveal the mechanisms underlying trimethyltin chloride-induced epilepsy and the ameliorative effects of astaxanthin via NFKB1 and IL6. | Ecotoxicol Environ Saf | 2026 | 42810259 | PubTator, text mining | PubMed |
| Association of metabotropic glutamate receptor 7 gene with nicotine dependence in a Chinese Han population: A cross-sectional candidate-gene association study. | Tob Induc Dis | 2026 | 42569468 | PubTator, text mining | PubMed |
Retraction notice to "UBTD2 protein molecules emerges as a key prognostic protein marker in glioma: Insights from integrated omics and machine learning analysis of GRM7, NCAPG, CEP55, and other biomarkers" [Int. J. Biol. Macromol. 310 (2025) 143473]. | Int J Biol Macromol | 2026 | 42527167 | PubTator, text mining | PubMed |
| Molecular pharmacology of mGlu7/8 heterodimers reveals unique properties of orthosteric agonists and positive allosteric modulators. | Mol Pharmacol | 2026 | 42385300 | PubTator, text mining | PubMed |
| Inflammation-associated alterations in mGluR transcript expression in the human nucleus accumbens independent of schizophrenia diagnosis. | Schizophr Res | 2026 | 42364358 | PubTator, text mining | PubMed |
| A Novel Intracellular Domain Missense Variant in GRM7 Associated with Early-Onset Neurodevelopmental Encephalopathy. | Mol Syndromol | 2026 | 42358513 | PubTator, text mining | PubMed |
| Therapeutic potential of metabotropic glutamate receptor 7 modulation in correcting cognitive deficits of schizophrenia. | Schizophr Res | 2026 | 42308865 | PubTator, text mining | PubMed |
| Family-Based GWAS of Cognitive Endophenotypes Reveals Genetic Architecture of Memory and Executive Function in Alzheimer's Disease. | Curr Issues Mol Biol | 2026 | 42193047 | PubTator, text mining | PubMed |
| Structural basis for the synaptic adhesion protein ELFN1-mediated modulation of mGlu7. | Protein Cell | 2026 | 42172605 | PubTator, text mining | PubMed |
| Metabotropic glutamate receptors in the testis: An integrative bioinformatic review of neuroendocrine, reproductive, and Neuropsychopharmacological aspects. | Prog Neuropsychopharmacol Biol Psychiatry | 2026 | 42134565 | PubTator, text mining | PubMed |
1 to 10 of 1,307
See all 1,307 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2917
GET https://conductscience.org/api/genes/v1/2917/patents?page=2