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Gene · 2925

GRPR: gastrin releasing peptide receptor

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GRPR: gastrin releasing peptide receptor. Genes, record 2925. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2925

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Gene

Symbol
GRPR
HGNC
Name
gastrin releasing peptide receptor
HGNC
NCBI Gene ID
2925
NCBI Gene
HGNC ID
HGNC:4609
HGNC
Ensembl
ENSG00000126010
NCBI Gene
Aliases
BB2, BB2R, BRS2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P30550Gastrin-releasing peptide receptor3844Ensembl, GeneID, HGNC

Source UniProt

Patents31

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1447395P30550Espacenet
JP 2025529142 A2025-09-041890P30550Espacenet
US 12371689 B22025-07-291890P30550Espacenet
US 11446398 B22022-09-2034198P30550Espacenet
US 11400116 B22022-08-023271P30550Espacenet
JP 2022524081 A2022-04-27137169P30550Espacenet
US 11078247 B22021-08-034749P30550Espacenet
US 10772934 B22020-09-151078P30550Espacenet
US 10292374 B22019-05-21580P30550Espacenet
JP 2019054813 A2019-04-11227830P30550Espacenet

1 to 10 of 31

See all 31 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants898

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGRPR papersNewest fiscal year
ZIADK053100Characterization And Pharmacology Of Receptors For Gastrointestinal Peptides272025
ZIADK053101Cellular Basis Of Action Of Gastrointestinal Peptides/Growth factors182025
P30CA008748Cancer Center Support Grant162025
P30EY010572Ophthalmology Core Facility122025
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)72025
ZIADE000721Molecular Genetic Studies of Somatosensation72025
P30CA016058Cancer Center Support Grant62025
P50CA097190Head and Neck Cancer SPORE62025
R01CA134675Enhanced imaging and treatment of aggressive subtypes of prostate cancer62025
ZIAEY000255Molecular Structure and Function of Crystallins62025

1 to 10 of 898Source NIH's project files

See all 898 nih grants

Papers2,036

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A molecular and spinal circuit basis for the functional segregation of itch and pain.Neuron202642805184PubTator, text miningPubMed
Targeted radionuclide-drug conjugates: Current status and perspectives.Eur J Med Chem202642520735PubTator, text miningPubMed
GRPR-Targeted Radionuclide Conjugates: A Molecular Evolution Perspective.Chem Biodivers202642520170PubTator, text miningPubMed
Design, Synthesis, and Preclinical Evaluation of Novel Dimeric RM2-Based Radioligands for GRPR-Targeted Breast Cancer Imaging.Mol Pharm202642479469PubTator, text miningPubMed
The gastrin-releasing peptide receptor in oncology: a comprehensive review of recent advances in targeted radionuclide theranostics.Front Oncol202642339117PubTator, text miningPubMed
Spinal and supraspinal mechanisms of chronic itch: from neuronal circuits to the neuro-immune-microbial axis.Front Med (Lausanne)202642311882PubTator, text miningPubMed
First-in-human radiation dosimetry of the GRPR antagonist [68Ga]Ga-NOTA-PEG2-RM26 in patients with prostate and breast cancer.EJNMMI Res202642310173PubTator, text miningPubMed
Clinical Value of 68 Ga-DOTA-Bombesin PET/CT Compared With 18 F-FDG PET/CT in the Staging of Breast Cancer.Clin Nucl Med202642305081PubTator, text miningPubMed
Evolution of PSMA-GRPr heterobivalent radiolabeled conjugates for the diagnosis and therapy of prostate cancer.Eur J Med Chem202642235186PubTator, text miningPubMed
Multivalent antibody-based conjugates as new tools for tailored modulation of G protein-coupled receptors.Br J Pharmacol202642225334PubTator, text miningPubMed

1 to 10 of 2,036

See all 2,036 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2925

GET https://conductscience.org/api/genes/v1/2925/patents?page=2