Gene · 2937
GSS: glutathione synthetase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. GSS: glutathione synthetase. Genes, record 2937. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2937
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P48637 | Glutathione synthetase | 474 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents40
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026067851 A | 2026-04-21 | 159 | P48637 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 47933 | P48637 | Espacenet |
| KR 1020250176604 A | 2025-12-22 | 2 | P48637 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 19372 | P48637 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 19372 | P48637 | Espacenet |
| US 11718832 B2 | 2023-08-08 | 13 | P48637 | Espacenet |
| JP 2023521663 A | 2023-05-25 | 158 | P48637 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 35423 | P48637 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 138394 | P48637 | Espacenet |
| JP 2021530985 A | 2021-11-18 | 266 | P48637 | Espacenet |
1 to 10 of 40
See all 40 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,320
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | GSS papers | Newest fiscal year |
|---|---|---|---|
| P30ES006694 | Southwest Environmental Health Sciences Center | 9 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 8 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 7 | 2025 |
| P30CA086862 | Cancer Center Support Grant | 7 | 2025 |
| R01ES010563 | Mechanisms of Manganese Neurotoxicity | 7 | 2025 |
| P42ES013661 | Iowa Superfund Research Program: Airborne PCBs: Sources, Exposures, Toxicities, Remediation | 6 | 2025 |
| R01ES007331 | Mechanisms of Methylmercury Induced Neuronal Toxicity | 6 | 2025 |
| P30CA006927 | Comprehensive Cancer Center Program at Fox Chase | 4 | 2025 |
| P30ES005605 | Environmental Health Sciences Research Center | 4 | 2025 |
| P30ES007048 | Environmental Exposures, Host Factors and Human Disease | 4 | 2025 |
1 to 10 of 1,320Source NIH's project files
See all 1,320 nih grantsPapers2,985
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Targeting GSS-mediated glutathione synthesis: 6-Met induces oxidative stress dependent apoptosis via triggering mitochondrial bioenergetics metabolism crisis and mTOR suppression in glioblastoma. | Redox Biol | 2026 | 42617573 | PubTator, text mining | PubMed |
| Multi-omics analysis of the rhizosphere effects and molecular mechanisms of Ageratum conyzoides linn. at different stages of Cd, Pb, and Zn co-stress. | J Environ Manage | 2026 | 42485963 | PubTator, text mining | PubMed |
| Redox Imbalance and Impaired Protein Clearance Drive Chronic Liver Injury in Biliary Atresia. | J Surg Res | 2026 | 42419058 | PubTator, text mining | PubMed |
| Shared genetic architecture of Parkinson's disease and cutaneous melanoma: Heterogeneous pleiotropy and Colocalization at the SOX6 locus. | Prog Neuropsychopharmacol Biol Psychiatry | 2026 | 42335983 | PubTator, text mining | PubMed |
| Cell size modulates ferroptosis susceptibility. | Elife | 2026 | 42267631 | PubTator, text mining | PubMed |
| Capsaicin acts as a novel NRF2 agonist to suppress ethanol induced gastric mucosa oxidative damage by directly disrupting the KEAP1-NRF2 interaction. | Elife | 2026 | 42262974 | PubTator, text mining | PubMed |
The role of STAT3-targeted therapy created with COLIVELIN in the cross-talk between IL6/JAK2/STAT3 and TGF-β/SMAD2/SMAD3 signaling in a hyperinflammation and ROS-induced in vitro AMD model and its effect on retinal apoptosis. | Int Ophthalmol | 2026 | 42240907 | PubTator, text mining | PubMed |
| Lens tissue transcriptome analysis in patients with total congenital cataract. | Hum Genomics | 2026 | 42192484 | PubTator, text mining | PubMed |
| Novel NSAID Analogs Exhibit Anti-Leukemic Activity Through Modulation of Apoptotic and Survival Pathways. | Int J Mol Sci | 2026 | 42123436 | PubTator, text mining | PubMed |
| Impaired pathways of detoxification and risk of Alzheimer's disease: Differential gene expression studies via gene set expression analysis. | J Alzheimers Dis Rep | 2026 | 42079451 | PubTator, text mining | PubMed |
1 to 10 of 2,985
See all 2,985 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2937
GET https://conductscience.org/api/genes/v1/2937/patents?page=2