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GSTP1: glutathione S-transferase pi 1

1 protein, 93 patents, 2 drugs, 8 trials, 4,037 NIH grants and 10,507 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolGSTP1HGNC
Nameglutathione S-transferase pi 1HGNC
NCBI Gene ID2950NCBI Gene
HGNC IDHGNC:4638HGNC
EnsemblENSG00000084207NCBI Gene
AliasesDFN7, FAEES3, GST3, GSTP, GSTP1-1, HEL-S-22, PINCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P09211Glutathione S-transferase P21068Ensembl, GeneID, HGNCUniProt

Patents 93

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1911611P09211Espacenet
EP 4641202 A22025-10-295995P09211Espacenet
US 12433933 B22025-10-0719P09211Espacenet
JP 2025517970 A2025-06-1211611P09211Espacenet
KR 1020250017231 A2025-02-045995P09211Espacenet
JP 2024123008 A2024-09-106348P09211Espacenet
US 12011476 B22024-06-1817P09211Espacenet
US 11771740 B22023-10-0319P09211Espacenet
JP 2023513371 A2023-03-301P09211Espacenet
JP 2022177146 A2022-11-302P09211Espacenet

Drugs 2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
EZATIOSTATCHEMBL2110585Glutathione S-transferase Pi inhibitorINHIBITORChEMBL
EZATIOSTAT HYDROCHLORIDECHEMBL2103810Glutathione S-transferase Pi inhibitorINHIBITORChEMBL

Trials 8

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT01459159EZATIOSTAT HYDROCHLORIDEPHASE2ClinicalTrials.gov
NCT01422486EZATIOSTAT HYDROCHLORIDEPHASE2ClinicalTrials.gov
NCT01062152EZATIOSTAT HYDROCHLORIDEPHASE1ClinicalTrials.gov
NCT00909584EZATIOSTAT HYDROCHLORIDEPHASE2ClinicalTrials.gov
NCT00701870EZATIOSTAT HYDROCHLORIDEPHASE2ClinicalTrials.gov
NCT00700206EZATIOSTAT HYDROCHLORIDEPHASE2ClinicalTrials.gov
NCT00280631EZATIOSTAT HYDROCHLORIDEPHASE1/PHASE2ClinicalTrials.gov
NCT00035867EZATIOSTAT HYDROCHLORIDEPHASE1/PHASE2ClinicalTrials.gov

NIH grants 4037

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant352,025NIH's project files
P30CA006973Regional Oncology Research Center342,025NIH's project files
P30ES009089Center for Environmental Health in Northern Manhattan342,025NIH's project files
P30ES010126UNC Center for Environmental Health and Susceptibility322,025NIH's project files
P30ES007048Environmental Exposures, Host Factors and Human Disease282,025NIH's project files
P30CA008748Cancer Center Support Grant222,025NIH's project files
P30ES007033University of Washington Interdisciplinary Center for Exposures, Diseases, Genomics & Environment222,025NIH's project files
R01EY011600Biochemistry and Pharmacology of the Macular Carotenoids222,025NIH's project files
P30ES005022Rutgers Center for Environmental Exposure and Disease (CEED)212,025NIH's project files
P30EY014800University of Utah Core Vision Research Grant192,025NIH's project files

Papers 10507

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818793PubTator, text miningPubMed
42815679PubTator, text miningPubMed
42803268PubTator, text miningPubMed
42794731PubTator, text miningPubMed
42756919PubTator, text miningPubMed
42747498PubTator, text miningPubMed
42697283PubTator, text miningPubMed
42689117PubTator, text miningPubMed
42669272PubTator, text miningPubMed
42648416PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license