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MSH6: mutS homolog 6

1 protein, 76 patents, 0 drugs, 0 trials, 4,043 NIH grants and 12,777 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolMSH6HGNC
NamemutS homolog 6HGNC
NCBI Gene ID2956NCBI Gene
HGNC IDHGNC:7329HGNC
EnsemblENSG00000116062NCBI Gene
AliasesGTBP, GTMBP, HNPCC5, HSAP, LYNCH5, MMRCS3, MSH-6, p160NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P52701DNA mismatch repair protein Msh61,3608Ensembl, GeneID, HGNCUniProt

Patents 76

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-19887P52701Espacenet
EP 4641201 A22025-10-29626P52701Espacenet
JP 2025517969 A2025-06-12626P52701Espacenet
JP 2025517970 A2025-06-12887P52701Espacenet
EP 4464338 A22024-11-20351P52701Espacenet
JP 2024123008 A2024-09-107164P52701Espacenet
US 11976334 B22024-05-07170P52701Espacenet
JP 2023098973 A2023-07-1114P52701Espacenet
US 11680268 B22023-06-20351P52701Espacenet
JP 2023518280 A2023-04-2819P52701Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4043

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant2392,025NIH's project files
P30CA016672Cancer Center Support Grant1602,025NIH's project files
P30CA016058Cancer Center Support Grant862,025NIH's project files
P30CA006973Regional Oncology Research Center552,025NIH's project files
P30CA015704Cancer Center Support Grant492,025NIH's project files
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant412,025NIH's project files
U01CA167551Colon Cancer Family Registry Cohort392,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award342,025NIH's project files
R01GM050006Enzymology of Mismatch Repair in Yeast312,025NIH's project files
P01CA092584Structural Cell Biology of DNA Repair Machines272,025NIH's project files

Papers 12777

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42822083PubTator, text miningPubMed
42821536PubTator, text miningPubMed
42809727PubTator, text miningPubMed
42809083PubTator, text miningPubMed
42806009PubTator, text miningPubMed
42802819PubTator, text miningPubMed
42801369PubTator, text miningPubMed
42798309PubTator, text miningPubMed
42797298PubTator, text miningPubMed
42795000PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license