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GTF2E1: general transcription factor IIE subunit 1

1 protein, 15 patents, 0 drugs, 0 trials, 1,071 NIH grants and 5,582 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolGTF2E1HGNC
Namegeneral transcription factor IIE subunit 1HGNC
NCBI Gene ID2960NCBI Gene
HGNC IDHGNC:4650HGNC
EnsemblENSG00000153767NCBI Gene
AliasesFE, TF2E1, TFIIE-ANCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P29083General transcription factor IIE subunit 143948Ensembl, GeneID, HGNCUniProt

Patents 15

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-193211P29083Espacenet
EP 4641201 A22025-10-292781P29083Espacenet
JP 2025517969 A2025-06-122781P29083Espacenet
JP 2025517970 A2025-06-123211P29083Espacenet
US 11446398 B22022-09-2034405P29083Espacenet
JP 2022524081 A2022-04-27137376P29083Espacenet
US 11078247 B22021-08-034788P29083Espacenet
WO 2020043864 A12020-03-052544P29083Espacenet
JP 2019033757 A2019-03-0723081P29083Espacenet
JP 2017123847 A2017-07-2023081P29083Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 1071

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R01GM065313Low-Coordinate Synthetic Models for Iron-Sulfur Enzymes202,025NIH's project files
R01GM061153Biosynthesis and Reactivity of the Active Site of the FeFe Hydrogenases132,025NIH's project files
R01GM111097Biological Transition Metals112,025NIH's project files
R37GM050781Hydrogen Bonding Cavity Motifs About Metal Ions82,025NIH's project files
R01DK031450Mechanistic Intermediates in Copper Oxygenases and Oxidases62,025NIH's project files
UG1HD076465The University of North Carolina-Kinshasa School of Public Health Research Partnership in the Democratic Republic of Congo; a Model for Improving Women's and Children's Health Through Research62,025NIH's project files
UG1HD078439Boston University/Lata Medical Research Foundation Global Network for Women's Children's Health Research Unit62,025NIH's project files
P30CA016086Cancer Center Support Grant52,025NIH's project files
P42ES004940The DUST Center: Hazardous Dust in Drylands - Exposure, Health Impacts, and Mitigation52,025NIH's project files
R35GM127079Mechanisms of Iron-Containing Enzymes52,025NIH's project files

Papers 5582

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42808102PubTator, text miningPubMed
42785398PubTator, text miningPubMed
42750024PubTator, text miningPubMed
42724178PubTator, text miningPubMed
42570940PubTator, text miningPubMed
42471081PubTator, text miningPubMed
42446406PubTator, text miningPubMed
42073833PubTator, text miningPubMed
42023994PubTator, text miningPubMed
41952995PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license