Gene · 2969
GTF2I: general transcription factor IIi
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. GTF2I: general transcription factor IIi. Genes, record 2969. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2969
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P78347 | General transcription factor II-I | 998 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents39
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 47519 | P78347 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 17343 | P78347 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 21408 | P78347 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15060 | P78347 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 21408 | P78347 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 17343 | P78347 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15060 | P78347 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15060 | P78347 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 14899 | P78347 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 34473 | P78347 | Espacenet |
1 to 10 of 39
See all 39 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,154
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | GTF2I papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 11 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 8 | 2025 |
| P30CA051008 | Georgetown University Lombardi Comprehensive Cancer Center Support Grant | 4 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 3 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 3 | 2025 |
| P30DK020593 | Vanderbilt Diabetes Research Center | 3 | 2025 |
| P50HD103525 | WASHINGTON UNIVERSITY INTELLECTUAL AND DEVELOPMENTAL DISABILITIES RESEARCH CENTER | 3 | 2025 |
| T32MH019908 | Research Training for Child Psychiatry and Neurodevelopment | 3 | 2025 |
| U54GM104938 | Oklahoma Shared Clinical and Translational Resources | 3 | 2025 |
| K12GM068524 | San Diego IRACDA Scholars Program | 2 | 2025 |
1 to 10 of 1,154Source NIH's project files
See all 1,154 nih grantsPapers1,337
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Genetic Heterogeneity in Autism Spectrum Disorder: Diagnostic Yield, Recurrent Genes, and Rare Variant-Phenotype Associations from Whole-Exome Sequencing. | Int J Mol Sci | 2026 | 42589554 | PubTator, text mining | PubMed |
| Yes-Associated Protein (YAP)1 and β-Catenin Immunohistochemistry as a Surrogate Marker for GTF2I-Mutant Type A/AB Thymomas. | Mod Pathol | 2026 | 42586240 | PubTator, text mining | PubMed |
| Modification of the Transcription Factor FOXL2 at Serines 101 and 107 Disables DNA Binding, Leads to Nucleolar Relocalization, and Rewires Granulosa-Cell Programs. | FASEB J | 2026 | 42541334 | PubTator, text mining | PubMed |
| [Clinicopathological analysis of 28 cases of micronodular thymic tumours with lymphoid stromal hyperplasia]. | Zhonghua Zhong Liu Za Zhi | 2026 | 42477929 | PubTator, text mining | PubMed |
| The glutathione transferase omega 1-1 GSTO1∗A140D polymorphism is associated with unfavourable prognosis in patients with thymoma and myasthenia gravis. | Adv Med Sci | 2026 | 42303225 | PubTator, text mining | PubMed |
| Distinct Associations of GTF2I, TP53, and NOTCH1 Variants with Indolent and Aggressive Thymic Epithelial Tumors in Vietnamese Patients. | Genes (Basel) | 2026 | 42194981 | PubTator, text mining | PubMed |
| Immune-related markers define clinically relevant prognostic subgroups in thymic epithelial tumors. | Lung Cancer | 2026 | 42091015 | PubTator, text mining | PubMed |
| The ZMIZ1-GTF2I interaction as a potential contributor to the neurodevelopmental phenotype in neurodevelopmental disorder with dysmorphic facies and distal skeletal anomalies (NEDDFSA). | Pediatr Res | 2026 | 41981097 | PubTator, text mining | PubMed |
| Plasma heme pool compartmentalization is linked to pathophysiology in Sickle Cell Disease. | PLoS One | 2026 | 41886505 | PubTator, text mining | PubMed |
| Modeling Williams syndrome from a neurodevelopmental perspective: recent advances, model-based translational insights and future directions. | World J Pediatr | 2026 | 41845159 | PubTator, text mining | PubMed |
1 to 10 of 1,337
See all 1,337 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2969
GET https://conductscience.org/api/genes/v1/2969/patents?page=2