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Gene · 30

ACAA1: acetyl-CoA acyltransferase 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ACAA1: acetyl-CoA acyltransferase 1. Genes, record 30. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/30

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Gene

Symbol
ACAA1
HGNC
Name
acetyl-CoA acyltransferase 1
HGNC
NCBI Gene ID
30
NCBI Gene
HGNC ID
HGNC:82
HGNC
Ensembl
ENSG00000060971
NCBI Gene
Aliases
ACAA, Lnc-Myd88, PTHIO, THIO
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P091103-ketoacyl-CoA thiolase, peroxisomal4242Ensembl, GeneID, HGNC

Source UniProt

Patents33

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1436003P09110Espacenet
EP 4650780 A22025-11-196036P09110Espacenet
JP 2025517970 A2025-06-126036P09110Espacenet
JP 2025062604 A2025-04-141241P09110Espacenet
US 11884978 B22024-01-30419P09110Espacenet
US 11446398 B22022-09-201241P09110Espacenet
JP 2022524081 A2022-04-27104212P09110Espacenet
EP 3504344 A12019-07-03606P09110Espacenet
JP 2019054813 A2019-04-11216438P09110Espacenet
EP 3258268 A12017-12-20130P09110Espacenet

1 to 10 of 33

See all 33 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants408

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleACAA1 papersNewest fiscal year
P30DK020572Michigan Diabetes Research Center (MDRC)22025
ZIABC005708Xenobiotic metabolism, cancer chemoprevention and cancer biomarkers22025
ZIACP010135Studies of Non-Ionizing Radiation-Related Cancer22025
DP2AI164325Using three-dimensional protein networks to uncover immuno-modulatory molecular phenotypes in infectious disease12025
K12CA090354Training Program in Nervous System Tumors12025
K23DK135414Adipose Tissue T Cell Polarization and Metabolic Health in Persons Living with HIV12025
K23HL156759Anti-cytomegalovirus Immune Responses in Atherosclerotic Cardiovascular Disease in Persons Living with HIV12025
KL2TR002245Institutional Career Development Core12025
P01AG036675Kynurenine accumulation drives loss of muscle and bone function with aging12025
P01CA013106Targeting Transcription and Splicing in Cancer12025

1 to 10 of 408Source NIH's project files

See all 408 nih grants

Papers591

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A Mitochondrial-Related Gene Signature for Diagnosis and Immune Microenvironment Modulation in Lung Cancer and Venous Thromboembolism.World J Oncol202642730163PubTator, text miningPubMed
Dynamic process of lipid deterioration in hickory: Mechanism analysis of metabolic imbalance, membrane damage and repair dysfunction based on multi-omics.Food Chem202642679476PubTator, text miningPubMed
iTRAQ- and MRM-Based Proteomics Identify Early Injury Biomarkers for Primary Dysfunction After Liver Transplantation.Ann Transplant202642444103PubTator, text miningPubMed
Profiling of immunomodulatory anti-cytokine autoantibodies associated with disease heterogeneity in a multiethnic Asian cohort.Sci Rep202642324287PubTator, text miningPubMed
ACAA1 mediates arachidonic acid dysregulation and membrane phospholipid remodeling to promote crystal-cell adhesion and ferroptosis susceptibility in calcium oxalate kidney stone.J Pharm Anal202642181662PubTator, text miningPubMed
Plasma Proteomic Signatures of Glucose Metabolism Disturbances and Early Diabetes.Int J Mol Sci202642123427PubTator, text miningPubMed
Aimed at Subtype Discrimination but Yielding a Shared Marker: Integrative Analysis of Blood Transcriptomes Reveals Upregulated TLR5 as a Potential Biomarker for IBD.Clin Exp Gastroenterol202642112146PubTator, text miningPubMed
Cell type-specific alterations in fatty acid metabolism in neuronal subpopulations of schizophrenia and construction of a diagnostic model.Front Psychiatry202642094829PubTator, text miningPubMed
The molecular glue CLEO4-88 inhibits the ACAA1 thiolase by induced binding to GID4.Nat Chem Biol202641957281PubTator, text miningPubMed
HCCaging: a liver physiological aging-related biomarker for hepatocellular carcinoma diagnosis based on transcriptome data.NPJ Aging202641942446PubTator, text miningPubMed

1 to 10 of 591

See all 591 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/30

GET https://conductscience.org/api/genes/v1/30/patents?page=2