Gene · 30
ACAA1: acetyl-CoA acyltransferase 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ACAA1: acetyl-CoA acyltransferase 1. Genes, record 30. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/30
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P09110 | 3-ketoacyl-CoA thiolase, peroxisomal | 424 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents33
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 36003 | P09110 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 6036 | P09110 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 6036 | P09110 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 1241 | P09110 | Espacenet |
| US 11884978 B2 | 2024-01-30 | 419 | P09110 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 1241 | P09110 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 104212 | P09110 | Espacenet |
| EP 3504344 A1 | 2019-07-03 | 606 | P09110 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 216438 | P09110 | Espacenet |
| EP 3258268 A1 | 2017-12-20 | 130 | P09110 | Espacenet |
1 to 10 of 33
See all 33 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants408
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ACAA1 papers | Newest fiscal year |
|---|---|---|---|
| P30DK020572 | Michigan Diabetes Research Center (MDRC) | 2 | 2025 |
| ZIABC005708 | Xenobiotic metabolism, cancer chemoprevention and cancer biomarkers | 2 | 2025 |
| ZIACP010135 | Studies of Non-Ionizing Radiation-Related Cancer | 2 | 2025 |
| DP2AI164325 | Using three-dimensional protein networks to uncover immuno-modulatory molecular phenotypes in infectious disease | 1 | 2025 |
| K12CA090354 | Training Program in Nervous System Tumors | 1 | 2025 |
| K23DK135414 | Adipose Tissue T Cell Polarization and Metabolic Health in Persons Living with HIV | 1 | 2025 |
| K23HL156759 | Anti-cytomegalovirus Immune Responses in Atherosclerotic Cardiovascular Disease in Persons Living with HIV | 1 | 2025 |
| KL2TR002245 | Institutional Career Development Core | 1 | 2025 |
| P01AG036675 | Kynurenine accumulation drives loss of muscle and bone function with aging | 1 | 2025 |
| P01CA013106 | Targeting Transcription and Splicing in Cancer | 1 | 2025 |
1 to 10 of 408Source NIH's project files
See all 408 nih grantsPapers591
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A Mitochondrial-Related Gene Signature for Diagnosis and Immune Microenvironment Modulation in Lung Cancer and Venous Thromboembolism. | World J Oncol | 2026 | 42730163 | PubTator, text mining | PubMed |
| Dynamic process of lipid deterioration in hickory: Mechanism analysis of metabolic imbalance, membrane damage and repair dysfunction based on multi-omics. | Food Chem | 2026 | 42679476 | PubTator, text mining | PubMed |
| iTRAQ- and MRM-Based Proteomics Identify Early Injury Biomarkers for Primary Dysfunction After Liver Transplantation. | Ann Transplant | 2026 | 42444103 | PubTator, text mining | PubMed |
| Profiling of immunomodulatory anti-cytokine autoantibodies associated with disease heterogeneity in a multiethnic Asian cohort. | Sci Rep | 2026 | 42324287 | PubTator, text mining | PubMed |
| ACAA1 mediates arachidonic acid dysregulation and membrane phospholipid remodeling to promote crystal-cell adhesion and ferroptosis susceptibility in calcium oxalate kidney stone. | J Pharm Anal | 2026 | 42181662 | PubTator, text mining | PubMed |
| Plasma Proteomic Signatures of Glucose Metabolism Disturbances and Early Diabetes. | Int J Mol Sci | 2026 | 42123427 | PubTator, text mining | PubMed |
| Aimed at Subtype Discrimination but Yielding a Shared Marker: Integrative Analysis of Blood Transcriptomes Reveals Upregulated TLR5 as a Potential Biomarker for IBD. | Clin Exp Gastroenterol | 2026 | 42112146 | PubTator, text mining | PubMed |
| Cell type-specific alterations in fatty acid metabolism in neuronal subpopulations of schizophrenia and construction of a diagnostic model. | Front Psychiatry | 2026 | 42094829 | PubTator, text mining | PubMed |
| The molecular glue CLEO4-88 inhibits the ACAA1 thiolase by induced binding to GID4. | Nat Chem Biol | 2026 | 41957281 | PubTator, text mining | PubMed |
| HCCaging: a liver physiological aging-related biomarker for hepatocellular carcinoma diagnosis based on transcriptome data. | NPJ Aging | 2026 | 41942446 | PubTator, text mining | PubMed |
1 to 10 of 591
See all 591 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/30
GET https://conductscience.org/api/genes/v1/30/patents?page=2