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GZMA: granzyme A

1 protein, 49 patents, 0 drugs, 0 trials, 3,498 NIH grants and 5,680 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolGZMAHGNC
Namegranzyme AHGNC
NCBI Gene ID3001NCBI Gene
HGNC IDHGNC:4708HGNC
EnsemblENSG00000145649NCBI Gene
AliasesCTLA3, HFSPNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P12544Granzyme A2623Ensembl, GeneID, HGNCUniProt

Patents 49

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1448203P12544Espacenet
EP 4650780 A22025-11-192899P12544Espacenet
EP 4641201 A22025-10-292463P12544Espacenet
JP 2025147176 A2025-10-066343P12544Espacenet
JP 2025529142 A2025-09-046562P12544Espacenet
US 12371689 B22025-07-296562P12544Espacenet
JP 2025517969 A2025-06-122463P12544Espacenet
JP 2025517970 A2025-06-122899P12544Espacenet
JP 2025041681 A2025-03-2652P12544Espacenet
JP 2025028160 A2025-02-286343P12544Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3498

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant462,025NIH's project files
P30CA016672Cancer Center Support Grant432,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award282,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant222,025NIH's project files
P30CA016520Abramson Cancer Center Support Grant172,025NIH's project files
U19AI082630Durable Alteration of the Human Immune system after Infection or Immunotherapy142,025NIH's project files
P50CA101942DF/HCC Kidney Cancer SPORE (supplement)132,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program112,025NIH's project files
P30AI027763UCSF-Bay Area Center for AIDS Research102,025NIH's project files
P30CA086862Cancer Center Support Grant92,025NIH's project files

Papers 5680

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42824708PubTator, text miningPubMed
42818212PubTator, text miningPubMed
42762643PubTator, text miningPubMed
42735597PubTator, text miningPubMed
42735032PubTator, text miningPubMed
42693941PubTator, text miningPubMed
42638197PubTator, text miningPubMed
42611377PubTator, text miningPubMed
42549226PubTator, text miningPubMed
42511524PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license