Gene · 3004
GZMM: granzyme M
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. GZMM: granzyme M. Genes, record 3004. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3004
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P51124 | Granzyme M | 257 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents24
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 48212 | P51124 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 2366 | P51124 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 6358 | P51124 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6566 | P51124 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6566 | P51124 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 2366 | P51124 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 6358 | P51124 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 6358 | P51124 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 6365 | P51124 | Espacenet |
| JP 2023123507 A | 2023-09-05 | 282 | P51124 | Espacenet |
1 to 10 of 24
See all 24 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants957
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | GZMM papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 7 | 2025 |
| P01CA100730 | Retrovirus Models of Cancer | 6 | 2025 |
| P30CA093373 | Cancer Center Support Grant P30 | 6 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 6 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 5 | 2025 |
| P30CA013330 | Cancer Center Support Grant | 4 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 4 | 2025 |
| ZIABC011255 | Genetic Modifiers of Initiation and Progression of Mammary Cancer | 4 | 2025 |
| I01BX003824 | Advanced conformational changes in NOTCH3 and cerebrovascular disease severity | 3 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 957Source NIH's project files
See all 957 nih grantsPapers1,329
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Excess Met1-linked ubiquitination leads to solid aggregate formation. | EMBO J | 2026 | 42806159 | PubTator, text mining | PubMed |
| Integrative single-cell and bulk transcriptomic profiling identify peripheral T-cell-associated candidate biomarkers in community-acquired pneumonia. | Int J Med Sci | 2026 | 42694836 | PubTator, text mining | PubMed |
| OTULIN: a master regulator of linear ubiquitin homeostasis in immune signaling, inflammation, and disease. | Front Immunol | 2026 | 42621935 | PubTator, text mining | PubMed |
| On the structure and function of granzymes, the deadly squad of cytotoxic lymphocytes. | Biol Chem | 2026 | 42439535 | PubTator, text mining | PubMed |
| Linear ubiquitin chain assembly complex contributes to NLRP3-mediated pyroptotic cell death. | iScience | 2026 | 42369039 | PubTator, text mining | PubMed |
| Ubiquitination of glycogen and metabolites in cells and tissues. | Nature | 2026 | 42020756 | PubTator, text mining | PubMed |
| Immunomodulatory Roles and Clinical Significance of GZMM and DDX24 in Sepsis: A Multiomics Integrative Analysis With Experimental Validation. | Hum Mutat | 2026 | 41948606 | PubTator, text mining | PubMed |
| Targeting pyroptosis to treat aortic aneurysms: From mechanism to drug discovery (Review). | Int J Mol Med | 2026 | 41930562 | PubTator, text mining | PubMed |
| DNA Methylation Dynamics in Plant Abiotic Stress Response: Mechanisms, Memory, and Breeding Applications. | Genes (Basel) | 2026 | 41898835 | PubTator, text mining | PubMed |
| Maternal opioid use disorder and hepatitis C infection in pregnancy reshape the peripheral immune landscape at term. | EBioMedicine | 2026 | 41849830 | PubTator, text mining | PubMed |
1 to 10 of 1,329
See all 1,329 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3004
GET https://conductscience.org/api/genes/v1/3004/patents?page=2