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Gene · 30061

SLC40A1: solute carrier family 40 member 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SLC40A1: solute carrier family 40 member 1. Genes, record 30061. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/30061

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Gene

Symbol
SLC40A1
HGNC
Name
solute carrier family 40 member 1
HGNC
NCBI Gene ID
30061
NCBI Gene
HGNC ID
HGNC:10909
HGNC
Ensembl
ENSG00000138449
NCBI Gene
Aliases
FPN, FPN1, HFE4, IREG1, MST079, MSTP079, MTP1, SLC11A3
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9NP59Ferroportin5718Ensembl, GeneID, HGNC

Source UniProt

Patents79

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-191840Q9NP59Espacenet
JP 2025169942 A2025-11-141290Q9NP59Espacenet
EP 4641202 A22025-10-2989Q9NP59Espacenet
JP 2025529142 A2025-09-044227Q9NP59Espacenet
US 12371689 B22025-07-294227Q9NP59Espacenet
JP 2025517970 A2025-06-121840Q9NP59Espacenet
KR 1020250017231 A2025-02-0489Q9NP59Espacenet
US 12000003 B22024-06-0454Q9NP59Espacenet
JP 2023049296 A2023-04-1039Q9NP59Espacenet
US 11446398 B22022-09-2081776Q9NP59Espacenet

1 to 10 of 79

See all 79 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,200

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSLC40A1 papersNewest fiscal year
ZIAHD001602Regulation Of Intracellular Iron Metabolism112025
P30CA062203Cancer Center Support Grant82025
R01ES010563Mechanisms of Manganese Neurotoxicity82025
P30ES006694Southwest Environmental Health Sciences Center72025
R01CA148828The role of HIF2alpha in colon carcinogenesis72025
P30CA086862Cancer Center Support Grant62025
R01DK095201Control of iron absorption by intestinal HIF2 in iron and hematological disorders62025
P30CA068485Cancer Center Support Grant52025
R35GM131919The mechanism and regulation of autophagy52025
P30CA008748Cancer Center Support Grant42025

1 to 10 of 1,200Source NIH's project files

See all 1,200 nih grants

Papers2,878

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Cascade-responsive biomimetic nanoparticles remodel tumor metabolism and potentiate ferroptosis for synergistic therapy of aggressive breast cancer.J Colloid Interface Sci202742574922PubTator, text miningPubMed
FPN1-8C>G Polymorphism as a potential genetic modifier of iron overload in transfusion-dependent β-Thalassemia major patients receiving HbF augmentation therapy.Pak J Med Sci202642819569PubTator, text miningPubMed
Single-Cell RNA Sequencing Combined with MEBOCOST Reveals Alveolar Macrophage-Mediated Immunometabolic Communication Mechanisms in Sepsis-Induced Acute Lung Injury.Genes (Basel)202642792913PubTator, text miningPubMed
DDR1 sustains ferroptosis resistance in pancreatic ductal adenocarcinoma via SLC40A1-mediated iron homeostasis.Oncogene202642778663PubTator, text miningPubMed
Ferroptosis-related genes influence AML risk through immune cell-mediated pathways: a Mendelian randomization study with mediation analysis.Blood Res202642766266PubTator, text miningPubMed
Realgar Transforming Solution Triggers Ferroptosis-Associated Death in NB4 Leukemia Cells through Disruption of Iron Homeostasis and Suppression of the SLC7A11/GPX4 Axis.Biol Pharm Bull202642716792PubTator, text miningPubMed
Diagnostic and Predictive Value of Circulating and Exosomal microRNAs in Ferroptosis-Associated Neurological Conditions: A Systematic Review and Meta-analysis.Mol Neurobiol202642704590PubTator, text miningPubMed
PEDV envelope protein promotes viral replication by remodeling host iron homeostasis via the TRIM28-KLF15-FPN axis.J Virol202642684901PubTator, text miningPubMed
Multi-Omics Integration Identifies Ferroptosis-Related miRNA-mRNA Networks and Independent Prognostic miRNAs in Triple-Negative Breast Cancer.J Clin Pract Res202642676387PubTator, text miningPubMed
Cross-cancer transcriptomic analysis reveals conserved developmental, ferroptosis, and immune remodeling modules in Wilms tumor and oral cancer.Front Genet202642670482PubTator, text miningPubMed

1 to 10 of 2,878

See all 2,878 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/30061

GET https://conductscience.org/api/genes/v1/30061/patents?page=2