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Gene · 3020

H3-3A: H3.3 histone A

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. H3-3A: H3.3 histone A. Genes, record 3020. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3020

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Gene

Symbol
H3-3A
HGNC
Name
H3.3 histone A
HGNC
NCBI Gene ID
3020
NCBI Gene
HGNC ID
HGNC:4764
HGNC
Ensembl
ENSG00000163041
NCBI Gene
Aliases
BRYLIB1, H3.3A, H3F3, H3F3A
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P84243Histone H3.3136103Ensembl, GeneID, HGNC

Source UniProt

Patents136

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026506083 A2026-02-20395P84243Espacenet
JP 2026004568 A2026-01-1448632P84243Espacenet
JP 2026004568 A2026-01-1448634P84243Espacenet
JP 2026004568 A2026-01-1448635P84243Espacenet
JP 2026004568 A2026-01-1448636P84243Espacenet
EP 4665855 A12025-12-24395P84243Espacenet
EP 4650780 A22025-11-191518P84243Espacenet
EP 4650780 A22025-11-1938940P84243Espacenet
EP 4650780 A22025-11-198114P84243Espacenet
EP 4641201 A22025-10-291132P84243Espacenet

1 to 10 of 136

See all 136 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,256

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleH3-3A papersNewest fiscal year
P30CA008748Cancer Center Support Grant402025
P30CA021765Cancer Center Support Grant (CCSG)302025
P01CA096832NORMAL & NEOPLASTIC GROWTH IN THE BRAIN232025
P30CA016672Cancer Center Support Grant212025
P50CA097257Brain Tumor SPORE Grant162025
P30CA006973Regional Oncology Research Center152025
R01NS076991Oligodendrocyte-focused rAAV gene therapy strategies for Canavan disease and Leukodystrophies112025
T32CA009676Training Program in Tumor Microenvironment92025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202882025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center62025

1 to 10 of 1,256Source NIH's project files

See all 1,256 nih grants

Papers2,385

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Exploring Molecular Pathways in Metastasis of Breast Cancer Cells to the Brain: Insights from Gene Expression Analysis and Cellular Origins.J Microsc Ultrastruct202642824931PubTator, text miningPubMed
H3F3B gene mutation in chondroblastomas: a multicenter study.Acta Orthop Traumatol Turc202642813348PubTator, text miningPubMed
Clinicopathological characteristics of giant cell tumor of bone and identification of a novel H3F3A p.V36_K37insL mutation.Pathol Res Pract202642743822PubTator, text miningPubMed
Exon-skipping antisense oligonucleotides for H3.3K27M-altered diffuse midline glioma therapy.Mol Ther Nucleic Acids202642656813PubTator, text miningPubMed
Sepsis-Induced Exosomal Transfer of MAFB mRNA Reprograms Hepatocytes via a miR-155-Jarid2-H3F3A Epigenetic Cascade.Cells202642645209PubTator, text miningPubMed
Xanthogranulomatous epithelial tumour of the calcaneus in a 32-year-old female: a rare entity.Skeletal Radiol202642552430PubTator, text miningPubMed
Clinical, surgical, and molecular characteristics and outcomes of adult patients with diffuse midline glioma, H3 K27-altered, treated with surgical resection.J Neurooncol202642390632PubTator, text miningPubMed
Incidence of malignant transformation in giant cell tumor of bone following denosumab therapy: a systematic review and meta-analysis.J Bone Oncol202642382831PubTator, text miningPubMed
The clinical and molecular landscape of thalamic glioma.Neuro Oncol202642377275PubTator, text miningPubMed
Needle-track metastasis in diffuse intrinsic pontine glioma: Need for a standardized surgical strategy?Neurooncol Adv202642368381PubTator, text miningPubMed

1 to 10 of 2,385

See all 2,385 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3020

GET https://conductscience.org/api/genes/v1/3020/patents?page=2