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Gene · 3028

HSD17B10: hydroxysteroid 17-beta dehydrogenase 10

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. HSD17B10: hydroxysteroid 17-beta dehydrogenase 10. Genes, record 3028. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3028

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Gene

Symbol
HSD17B10
HGNC
Name
hydroxysteroid 17-beta dehydrogenase 10
HGNC
NCBI Gene ID
3028
NCBI Gene
HGNC ID
HGNC:4800
HGNC
Ensembl
ENSG00000072506
NCBI Gene
Aliases
17b-HSD10, ABAD, CAMR, DUPXp11.22, ERAB, HADH2, HCD2, HSD10MD, MHBD, MRPP2, MRX17, MRX31, MRXS10, SCHAD, SDR5C1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q997143-hydroxyacyl-CoA dehydrogenase type-226115Ensembl, GeneID, HGNC

Source UniProt

Patents37

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1449547Q99714Espacenet
EP 4650780 A22025-11-19136Q99714Espacenet
JP 2025517970 A2025-06-12136Q99714Espacenet
US 11957687 B22024-04-1610Q99714Espacenet
JP 2024507735 A2024-02-21198Q99714Espacenet
US 11446398 B22022-09-2039298Q99714Espacenet
JP 2022524081 A2022-04-27142269Q99714Espacenet
KR 1020210152990 A2021-12-1621Q99714Espacenet
KR 1020210111195 A2021-09-1021Q99714Espacenet
KR 1020200040204 A2020-04-1721Q99714Espacenet

1 to 10 of 37

See all 37 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,003

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleHSD17B10 papersNewest fiscal year
P50CA097186The Pacific Northwest Prostate Cancer SPORE82025
R01GM117141Structural and functional basis for protein-based eukaryotic RNA processing62025
P01AG026572Perimenopause in Brain Aging and Alzheimer's Disease52025
P30CA008748Cancer Center Support Grant52025
P30CA016672Cancer Center Support Grant52025
P30AI094189The Johns Hopkins Center for AIDS Research (JHU CFAR)32025
P30CA013696Cancer Center Support Grant32025
P30CA015704Cancer Center Support Grant32025
P30CA016056Roswell Park Cancer Center Support Grant32025
P30CA033572Cancer Center Support Grant32025

1 to 10 of 1,003Source NIH's project files

See all 1,003 nih grants

Papers1,285

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Metabolomics-Driven Discovery of Targets for Hepatocytotoxicity Induced by Triphenyltin Chloride through Mitochondrial Function Involving HSD17B10 and HADH.Environ Health (Wash)202642774750PubTator, text miningPubMed
A Mitochondrial-Related Gene Signature for Diagnosis and Immune Microenvironment Modulation in Lung Cancer and Venous Thromboembolism.World J Oncol202642730163PubTator, text miningPubMed
Network pharmacology based identification of potential phytocompounds from Betula utilis in the treatment of leishmaniasis.J Parasit Dis202642670328PubTator, text miningPubMed
Integrated transcriptomic and tissue-validation analyses identify palmitoylation-associated biomarkers linked to sphingolipid metabolism and immune remodeling in psoriasis.Front Immunol202642553137PubTator, text miningPubMed
Development of Novel 17β-HSD10 Inhibitors and Their Evaluation in an In Vitro Model of Alzheimer's Disease.ACS Med Chem Lett202642305190PubTator, text miningPubMed
Oleuropein and hydroxytyrosol enhance mitochondrial function and biogenesis in SH-SY5Y cells through estrogen-like mechanisms.Food Funct202642299956PubTator, text miningPubMed
The inhibitors of 17β-HSD10: are they any good?RSC Chem Biol202642282265PubTator, text miningPubMed
High glucose impairs cognitive function by inducing lipid droplet accumulation through lactylation of HSD17B10 at K105.Cell Rep202642275213PubTator, text miningPubMed
Adult case of 17β-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency due to the p. Arg130Cys mutation of the HSD17B10 gene: case report.AME Case Rep202641971928PubTator, text miningPubMed
Alzheimer's disease: from molecular pathways to therapies.Mol Biomed202641925951PubTator, text miningPubMed

1 to 10 of 1,285

See all 1,285 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3028

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