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Gene · 3037

HAS2: hyaluronan synthase 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. HAS2: hyaluronan synthase 2. Genes, record 3037. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3037

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Gene

Symbol
HAS2
HGNC
Name
hyaluronan synthase 2
HGNC
NCBI Gene ID
3037
NCBI Gene
HGNC ID
HGNC:4819
HGNC
Ensembl
ENSG00000170961
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q92819Hyaluronan synthase 25520Ensembl, GeneID, HGNC

Source UniProt

Patents69

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1449461Q92819Espacenet
EP 4650780 A22025-11-194460Q92819Espacenet
JP 2025529142 A2025-09-041910Q92819Espacenet
US 12371689 B22025-07-291910Q92819Espacenet
JP 2025517970 A2025-06-124460Q92819Espacenet
JP 2025032204 A2025-03-1129486Q92819Espacenet
JP 2025013347 A2025-01-24155Q92819Espacenet
US 12201675 B22025-01-21155Q92819Espacenet
JP 2025003953 A2025-01-14155Q92819Espacenet
EP 4461818 A22024-11-1329486Q92819Espacenet

1 to 10 of 69

See all 69 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,467

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleHAS2 papersNewest fiscal year
R01DK085252Extracellular Matrix Regulates Hepatic Stellate Cell Activation and Fibrosis72025
P30CA016672Cancer Center Support Grant62025
P51OD011092Support for National Primate Research Center62025
P30CA077598Cancer Center Support Grant52025
P30EY007551Center Core Grant for Vision Research52025
ZIAES102605The Role of Hyaluronan And Inter-Alpha-Trypsin Inhibitor in Tissue Injury52025
P01AG047200Comparative genomics of longevity and Alzheimer's disease42025
P30CA006973Regional Oncology Research Center42025
P30CA013696Cancer Center Support Grant42025
P30CA142543UT Southwestern Medical Center Simmons Comprehensive Cancer Center42025

1 to 10 of 1,467Source NIH's project files

See all 1,467 nih grants

Papers2,533

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
5-oxoproline supplementation enhances maturation and developmental competence of low-quality porcine cumulus-oocyte complexes during in vitro maturation.Theriogenology202742748792PubTator, text miningPubMed
In Vitro and Clinical Dermatological Effects of Rubus crataegifolius Fruit Extracts on Human Fibroblasts and Keratinocytes.Pharmaceuticals (Basel)202642797496PubTator, text miningPubMed
Effect of Prostaglandin Analogues on Hyaluronan Production of Orbital Fibroblasts.Biomedicines202642792868PubTator, text miningPubMed
Integrative network toxicology and transcriptomic analyses identify DCP1B and HAS2 as key prognostic biomarkers in formaldehyde-associated Wilms tumor.J Int Med Res202642770314PubTator, text miningPubMed
YAP1 Is Associated with Cumulus Expansion-Related Factor Expression and Autophagy-Related Signaling in Yak Cumulus Cells.Animals (Basel)202642738425PubTator, text miningPubMed
Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review.FEBS Open Bio202642713832PubTator, text miningPubMed
Genomic Landscape of Systemic Lupus Erythematosus and Lupus Nephritis Globally and the Gaps in Africa.Int J Mol Sci202642653386PubTator, text miningPubMed
LTBP4 deficiency induces MRC1+/CD44+ macrophages to drive cancer progression in preclinical colorectal cancer models.Sci Transl Med202642647596PubTator, text miningPubMed
Integrative transcriptomic and single-cell analysis identifies anoikis-related molecular signatures in vascular calcification.Ren Fail202642634887PubTator, text miningPubMed
Hyaluronan deficiency disrupts endothelial glycocalyx integrity and contributes to age-related arterial dysfunction.Geroscience202642625099PubTator, text miningPubMed

1 to 10 of 2,533

See all 2,533 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3037

GET https://conductscience.org/api/genes/v1/3037/patents?page=2